2023
Detection of Intracerebral Hemorrhage Using Low-Field, Portable Magnetic Resonance Imaging in Patients With Stroke
Mazurek M, Parasuram N, Peng T, Beekman R, Yadlapalli V, Sorby-Adams A, Lalwani D, Zabinska J, Gilmore E, Petersen N, Falcone G, Sujijantarat N, Matouk C, Payabvash S, Sze G, Schiff S, Iglesias J, Rosen M, de Havenon A, Kimberly W, Sheth K. Detection of Intracerebral Hemorrhage Using Low-Field, Portable Magnetic Resonance Imaging in Patients With Stroke. Stroke 2023, 54: 2832-2841. PMID: 37795593, PMCID: PMC11103256, DOI: 10.1161/strokeaha.123.043146.Peer-Reviewed Original ResearchClinical implications of Peri-hematomal edema microperfusion fraction in intracerebral hemorrhage intravoxel incoherent motion imaging – A pilot study
Abou Karam G, Tharmaseelan H, Aboian M, Malhotra A, Gilmore E, Falcone G, de Havenon A, Sheth K, Payabvash S. Clinical implications of Peri-hematomal edema microperfusion fraction in intracerebral hemorrhage intravoxel incoherent motion imaging – A pilot study. Journal Of Stroke And Cerebrovascular Diseases 2023, 32: 107375. PMID: 37738914, PMCID: PMC10591892, DOI: 10.1016/j.jstrokecerebrovasdis.2023.107375.Peer-Reviewed Original ResearchConceptsModified Rankin ScaleSecondary brain injuryIntracerebral hemorrhagePerihematomal edemaSubacute intracerebral hemorrhageIntravoxel incoherent motion imagingAdmission NIHSSBrain injuryMedian baseline National InstitutesPilot studyBaseline National InstitutesHealth Stroke ScalePerfusion fractionSupratentorial intracerebral hemorrhageIVIM metricsIncoherent motion imagingStroke ScaleNeuroprotective therapiesParenchymal injuryRankin ScaleRisk patientsConsecutive patientsUnivariable analysisPoor outcomeICH volumeEmergent external ventricular drain placement in patients with factor Xa inhibitor-associated intracerebral hemorrhage after reversal with andexanet alfa
Ammar A, Elsamadicy A, Ammar M, Reeves B, Koo A, Falcone G, Hwang D, Petersen N, Kim J, Beekman R, Prust M, Magid-Bernstein J, Acosta J, Herbert R, Sheth K, Matouk C, Gilmore E. Emergent external ventricular drain placement in patients with factor Xa inhibitor-associated intracerebral hemorrhage after reversal with andexanet alfa. Clinical Neurology And Neurosurgery 2023, 226: 107621. PMID: 36791588, DOI: 10.1016/j.clineuro.2023.107621.Peer-Reviewed Original ResearchConceptsAndexanet alfaExtra-axial hemorrhageEVD placementThrombotic eventsNew hemorrhagePrimary safety outcomeExternal ventricular drain placementLarge prospective studiesIntensive care unitIntracerebral hemorrhage patientsVentricular drain placementBolus patientsHospital lengthHospital LOSICU LOSTract hemorrhageRankin scoreSecondary outcomesAdult patientsBolus groupPrimary outcomeCare unitIntracerebral hemorrhageLong administration timeHemorrhage patients
2017
Functional Improvement Among Intracerebral Hemorrhage (ICH) Survivors up to 12 Months Post-injury
Sreekrishnan A, Leasure AC, Shi FD, Hwang DY, Schindler JL, Petersen NH, Gilmore EJ, Kamel H, Sansing LH, Greer DM, Sheth KN. Functional Improvement Among Intracerebral Hemorrhage (ICH) Survivors up to 12 Months Post-injury. Neurocritical Care 2017, 27: 326-333. PMID: 28685394, PMCID: PMC5700855, DOI: 10.1007/s12028-017-0425-4.Peer-Reviewed Original Research
2016
Review of the Utility of Prophylactic Anticonvulsant Use in Critically Ill Patients With Intracerebral Hemorrhage
Gilmore EJ, Maciel CB, Hirsch LJ, Sheth KN. Review of the Utility of Prophylactic Anticonvulsant Use in Critically Ill Patients With Intracerebral Hemorrhage. Stroke 2016, 47: 2666-2672. PMID: 27608820, DOI: 10.1161/strokeaha.116.012410.Peer-Reviewed Original ResearchCritical Care Management of Intracerebral Hemorrhage
Morawo AO, Gilmore EJ. Critical Care Management of Intracerebral Hemorrhage. Seminars In Neurology 2016, 36: 225-232. PMID: 27214697, DOI: 10.1055/s-0036-1581991.Peer-Reviewed Original ResearchConceptsManagement of ICHIntracerebral hemorrhageMedical complicationsCare managementNeurocritical care managementSecondary brain injuryCritical care managementForm of strokeRole of imagingCritical care settingSpontaneous intracerebral hemorrhageLife-sustaining therapyMajor healthcare concernRisk factorsBrain injuryClinical trialsIntracranial pressureCare settingsEarly withdrawalHemorrhageHealthcare concernComplicationsPrognosisMajor targetIntensive monitoringIntracerebral Hemorrhage Location and Functional Outcomes of Patients: A Systematic Literature Review and Meta-Analysis
Sreekrishnan A, Dearborn JL, Greer DM, Shi FD, Hwang DY, Leasure AC, Zhou SE, Gilmore EJ, Matouk CC, Petersen NH, Sansing LH, Sheth KN. Intracerebral Hemorrhage Location and Functional Outcomes of Patients: A Systematic Literature Review and Meta-Analysis. Neurocritical Care 2016, 25: 384-391. PMID: 27160888, DOI: 10.1007/s12028-016-0276-4.Peer-Reviewed Original Research
2015
Time Course and Predictors of Neurological Deterioration After Intracerebral Hemorrhage
Lord AS, Gilmore E, Choi HA, Mayer SA. Time Course and Predictors of Neurological Deterioration After Intracerebral Hemorrhage. Stroke 2015, 46: 647-652. PMID: 25657190, PMCID: PMC4739782, DOI: 10.1161/strokeaha.114.007704.Peer-Reviewed Original ResearchConceptsNeurological deteriorationIntracerebral hemorrhage volumeHematoma expansionInterventricular hemorrhageIntracerebral hemorrhageHemorrhage volumeAdmission Glasgow Coma ScaleEarly neurological deteriorationLate neurological deteriorationAcute neurological deteriorationRetrospective cohort studyHours of symptomsGlasgow Coma ScaleIntracerebral hemorrhage trialsTime coursePlacebo patientsCerebral edemaDevastating complicationRankin scoreCohort studyComa ScaleMedical complicationsPoor outcomeTomographic scanClinical evaluation
2013
Improving ascertainment and communication of prognosis in intracerebral hemorrhage
Gilmore EJ, Sheth KN. Improving ascertainment and communication of prognosis in intracerebral hemorrhage. Critical Care 2013, 17: 1021. PMID: 24321182, PMCID: PMC4059379, DOI: 10.1186/cc13144.Peer-Reviewed Original Research
2010
Seizures and CNS Hemorrhage
Gilmore E, Choi HA, Hirsch LJ, Claassen J. Seizures and CNS Hemorrhage. The Neurologist 2010, 16: 165-175. PMID: 20445426, DOI: 10.1097/nrl.0b013e3181c7cd0b.Peer-Reviewed Original ResearchConceptsAneurysmal subarachnoid hemorrhageCentral nervous system hemorrhageShort-term prophylaxisNonconvulsive seizuresIntracerebral hemorrhageSpontaneous intracerebral hemorrhageSeizure prophylaxisASAH patientsAdditional injuriesAcute brain injuryPoor clinical gradeEvidence-based guidelinesCommon neurologic conditionsDeleterious effectsAntiepileptic medicationsControlled TrialsConvulsive seizuresCNS hemorrhagePoor outcomeSubarachnoid hemorrhageNeurologic conditionsSurrogate markerBrain injuryClinical gradeRecent injury