2005
Prevalence of BRCA1 and BRCA2 Mutations in Women Diagnosed With Ductal Carcinoma In Situ
Claus EB, Petruzella S, Matloff E, Carter D. Prevalence of BRCA1 and BRCA2 Mutations in Women Diagnosed With Ductal Carcinoma In Situ. JAMA 2005, 293: 964-969. PMID: 15728167, DOI: 10.1001/jama.293.8.964.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedBreast NeoplasmsCarcinoma, Intraductal, NoninfiltratingFemaleGenes, BRCA1Genes, BRCA2HumansMiddle AgedMutationConceptsInvasive breast cancerBreast cancerDuctal carcinomaFamily historyDCIS casesOvarian cancerBRCA2 mutationsBreast carcinomaLarge population-based case-control studyPopulation-based case-control studyFirst-degree family historyBreast/ovarian cancer syndromeBRCA2 mutation prevalenceHigh-risk protocolRisk factor informationNoninvasive breast carcinomaPrevalence of BRCA1Case-control studyOvarian cancer syndromeFirst-degree relativesBRCA2 mutation testingDisease-associated mutationsDistribution of BRCA1Mutation prevalenceCancer syndromes
1991
Genetic analysis of breast cancer in the cancer and steroid hormone study.
Claus EB, Risch N, Thompson WD. Genetic analysis of breast cancer in the cancer and steroid hormone study. American Journal Of Human Genetics 1991, 48: 232-42. PMID: 1990835, PMCID: PMC1683001.Peer-Reviewed Original ResearchConceptsCumulative lifetime riskBreast cancerLifetime riskSteroid Hormone StudyCase-control studyAge-specific riskBreast cancer casesProportion of casesInterviews of casesCancer casesFamily historyWomen's ageHormone StudyYounger ageCancerDisease controlGreater riskFamilial riskAgeSusceptibility allelesRiskNoncarriersAutosomal dominant alleleGenetic modelsYears