2022
Pilot Randomized Clinical Trial of a Goals-of-Care Decision Aid for Surrogates of Patients With Severe Acute Brain Injury
Muehlschlegel S, Goostrey K, Flahive J, Zhang Q, Pach JJ, Hwang DY. Pilot Randomized Clinical Trial of a Goals-of-Care Decision Aid for Surrogates of Patients With Severe Acute Brain Injury. Neurology 2022, 99: e1446-e1455. PMID: 35853748, PMCID: PMC9576301, DOI: 10.1212/wnl.0000000000200937.Peer-Reviewed Original ResearchConceptsCode status changeTraumatic brain injuryBrain injuryIschemic strokeCare decisionsIntracerebral hemorrhageDA groupAcute brain injury patientsSevere acute brain injuryNeurologic intensive care unitCare decision aidSurrogates of patientsAcute brain injuryAcute ischemic strokeClass IV evidenceLong-term prognosisIntensive care unitBrain injury patientsClinician-family communicationAdditional psychosocial supportPatient-centered careLife-sustaining treatmentPsychological outcomesDecision-making interventionClassification of evidence
2021
End-of-Life Care Decision-Making in Stroke
Gao L, Zhao C, Hwang D. End-of-Life Care Decision-Making in Stroke. Frontiers In Neurology 2021, 12: 702833. PMID: 34650502, PMCID: PMC8505717, DOI: 10.3389/fneur.2021.702833.Peer-Reviewed Original ResearchStroke patientsImmediate post-stroke periodIntensive care unit careLong-term functional outcomeCare decisionsCode status changePost-stroke periodIntensive care unitIntracerebral hemorrhage patientsLong-term disabilityLife care discussionsLife-sustaining therapyCause of deathLife care decisionsClinician's subjectivityIschemic strokeUnit careCare unitHemorrhage patientsPatient survivalFunctional outcomeProvider recommendationPatient preferencesCare discussionsTreatment goalsAdapting a Traumatic Brain Injury Goals-of-Care Decision Aid for Critically Ill Patients to Intracerebral Hemorrhage and Hemispheric Acute Ischemic Stroke
Goostrey KJ, Lee C, Jones K, Quinn T, Moskowitz J, Pach JJ, Knies AK, Shutter L, Goldberg R, Mazor KM, Hwang DY, Muehlschlegel S. Adapting a Traumatic Brain Injury Goals-of-Care Decision Aid for Critically Ill Patients to Intracerebral Hemorrhage and Hemispheric Acute Ischemic Stroke. Critical Care Explorations 2021, 3: e0357. PMID: 33786434, PMCID: PMC7994105, DOI: 10.1097/cce.0000000000000357.Peer-Reviewed Original ResearchAcute ischemic strokeCare decision aidIschemic strokeNeurologic ICUIntracerebral hemorrhageIll patientsIll traumatic brain injury patientsTraumatic brain injury patientsInternational Patient Decision Aid StandardsDisease-specific prognosisProspective observational studyBrain injury patientsIntracerebral Hemorrhage ScorePatient decision aidCare decision supportDecision aidDisease-specific dataOutcome prediction modelsDecision aid contentFamily membersHemorrhagic strokeInjury patientsFeasibility trialPatient prognosisObservational study
2018
Safety Outcomes of Thrombolysis for Acute Ischemic Stroke in Patients with History of Intracranial Hemorrhage (P4.033)
Chu S, Sommaruga S, Hwang D, Dearborn J, Sansing L, Cord B, Samarth G, Petersen N, Gilmore E, Schindler J, Matouk C, Sheth K, Falcone G. Safety Outcomes of Thrombolysis for Acute Ischemic Stroke in Patients with History of Intracranial Hemorrhage (P4.033). Neurology 2018, 90 DOI: 10.1212/wnl.90.15_supplement.p4.033.Peer-Reviewed Original Research
2016
Timing of Percutaneous Endoscopic Gastrostomy for Acute Ischemic Stroke
George BP, Kelly AG, Albert GP, Hwang DY, Holloway RG. Timing of Percutaneous Endoscopic Gastrostomy for Acute Ischemic Stroke. Stroke 2016, 48: 420-427. PMID: 27965430, DOI: 10.1161/strokeaha.116.015119.Peer-Reviewed Original ResearchConceptsAcute ischemic strokeTime-limited trialsNasogastric feedingIschemic strokePEG placementPercutaneous endoscopic gastrostomy (PEG) tube placementEndoscopic gastrostomy tube placementEarly PEG placementSurgical feeding tubeDay of admissionHigh-volume hospitalsPercutaneous endoscopic gastrostomyRetrospective observational studyIschemic stroke admissionsGastrostomy tube placementEffect of patientMultivariable regression analysisAdult age groupsOlder adult age groupsPEG recipientsEarly PEGEndoscopic gastrostomyStroke admissionsMedian timePEG tube