2022
Pilot Randomized Clinical Trial of a Goals-of-Care Decision Aid for Surrogates of Patients With Severe Acute Brain Injury
Muehlschlegel S, Goostrey K, Flahive J, Zhang Q, Pach JJ, Hwang DY. Pilot Randomized Clinical Trial of a Goals-of-Care Decision Aid for Surrogates of Patients With Severe Acute Brain Injury. Neurology 2022, 99: e1446-e1455. PMID: 35853748, PMCID: PMC9576301, DOI: 10.1212/wnl.0000000000200937.Peer-Reviewed Original ResearchConceptsCode status changeTraumatic brain injuryBrain injuryIschemic strokeCare decisionsIntracerebral hemorrhageDA groupAcute brain injury patientsSevere acute brain injuryNeurologic intensive care unitCare decision aidSurrogates of patientsAcute brain injuryAcute ischemic strokeClass IV evidenceLong-term prognosisIntensive care unitBrain injury patientsClinician-family communicationAdditional psychosocial supportPatient-centered careLife-sustaining treatmentPsychological outcomesDecision-making interventionClassification of evidenceStressors Experienced by Primary Caregivers of Severe Acute Brain Injury Patients Recovering from Coma in Neurointensive Care Units: Preliminary Findings from a Multicenter Qualitative Study (P1-4.009)
Meurer K, Kubota R, Baskaran N, Zhang Q, Bannon S, Fishbein N, Reichman M, Popok P, Lester E, Motta M, Muehlschlegel S, Reznik M, Jaffa M, Creutzfeldt C, Fehnel C, Williamson C, Vranceanu A, Hwang D, Investigators C. Stressors Experienced by Primary Caregivers of Severe Acute Brain Injury Patients Recovering from Coma in Neurointensive Care Units: Preliminary Findings from a Multicenter Qualitative Study (P1-4.009). Neurology 2022, 98 DOI: 10.1212/wnl.98.18_supplement.3641.Peer-Reviewed Original Research
2021
A Two-Center, Parallel-Arm Randomized-Controlled Feasibility Trial Of A Goals-Of-Care Decision Aid For Surrogates Of Severe Acute Brain Injury Patients (2288)
Muehlschlegel S, Goostrey K, Flahive J, Zhang Q, Pach J, Hwang D. A Two-Center, Parallel-Arm Randomized-Controlled Feasibility Trial Of A Goals-Of-Care Decision Aid For Surrogates Of Severe Acute Brain Injury Patients (2288). Neurology 2021, 96 DOI: 10.1212/wnl.96.15_supplement.2288.Peer-Reviewed Original ResearchAdapting a Traumatic Brain Injury Goals-of-Care Decision Aid for Critically Ill Patients to Intracerebral Hemorrhage and Hemispheric Acute Ischemic Stroke
Goostrey KJ, Lee C, Jones K, Quinn T, Moskowitz J, Pach JJ, Knies AK, Shutter L, Goldberg R, Mazor KM, Hwang DY, Muehlschlegel S. Adapting a Traumatic Brain Injury Goals-of-Care Decision Aid for Critically Ill Patients to Intracerebral Hemorrhage and Hemispheric Acute Ischemic Stroke. Critical Care Explorations 2021, 3: e0357. PMID: 33786434, PMCID: PMC7994105, DOI: 10.1097/cce.0000000000000357.Peer-Reviewed Original ResearchAcute ischemic strokeCare decision aidIschemic strokeNeurologic ICUIntracerebral hemorrhageIll patientsIll traumatic brain injury patientsTraumatic brain injury patientsInternational Patient Decision Aid StandardsDisease-specific prognosisProspective observational studyBrain injury patientsIntracerebral Hemorrhage ScorePatient decision aidCare decision supportDecision aidDisease-specific dataOutcome prediction modelsDecision aid contentFamily membersHemorrhagic strokeInjury patientsFeasibility trialPatient prognosisObservational studyPredictors of Surrogate Decision Makers Selecting Life-Sustaining Therapy for Severe Acute Brain Injury Patients: An Analysis of US Population Survey Data
Garg A, Soto AL, Knies AK, Kolenikov S, Schalk M, Hammer H, White DB, Holloway RG, Sheth KN, Fraenkel L, Hwang DY. Predictors of Surrogate Decision Makers Selecting Life-Sustaining Therapy for Severe Acute Brain Injury Patients: An Analysis of US Population Survey Data. Neurocritical Care 2021, 35: 468-479. PMID: 33619667, PMCID: PMC8380750, DOI: 10.1007/s12028-021-01200-9.Peer-Reviewed Original ResearchConceptsSevere acute brain injuryAcute brain injuryLife-sustaining treatmentSurrogate decision makersBrain injuryAcute brain injury patientsPatient's surrogate decision makersSevere disabilityPoor neurological prognosisIntensive care unitSevere brain injuryLife-Sustaining TherapyBrain injury patientsCost of careYounger age groupsCross-sectional survey studyUS population sampleBinary logistic regressionNeurological prognosisIndependent predictorsCare unitInjury patientsPoor prognosisMale genderUnivariate analysis
2020
Psychological Attachment Orientations of Surrogate Decision-Makers and Goals-of-Care Decisions for Brain Injury Patients in ICUs
Knies AK, Zhang Q, Juthani P, Tu S, Pach J, Martinez A, Monin JK, Hwang DY. Psychological Attachment Orientations of Surrogate Decision-Makers and Goals-of-Care Decisions for Brain Injury Patients in ICUs. Critical Care Explorations 2020, 2: e0151. PMID: 32696015, PMCID: PMC7340333, DOI: 10.1097/cce.0000000000000151.Peer-Reviewed Original ResearchLife-sustaining therapyBrain injury patientsAcute brain injury patientsInjury patientsTherapy selectionNonwhite racePoor prognosisFisher's exact testAcademic medical centerCross-sectional surveyNeuroscience ICUPatient demographicsIndependent predictorsMedical CenterComfort measuresExact testConsecutive samplePatientsEligible respondentsTherapyICUCare decisionsFuture interventionsMultivariate modelSignificant predictors