2009
Aripiprazole monotherapy in acute mania: 12-week randomised placebo- and haloperidol-controlled study
Young A, Oren D, Lowy A, McQuade R, Marcus R, Carson W, Spiller N, Torbeyns A, Sanchez R. Aripiprazole monotherapy in acute mania: 12-week randomised placebo- and haloperidol-controlled study. The British Journal Of Psychiatry 2009, 194: 40-48. PMID: 19118324, DOI: 10.1192/bjp.bp.108.049965.Peer-Reviewed Original ResearchConceptsWeek 12Young Mania Rating Scale (YMRS) total scoreDouble-blind aripiprazoleHaloperidol-treated patientsTolerability of aripiprazoleExtrapyramidal adverse eventsScale total scoreMasked treatmentAdverse eventsClinical improvementAcute maniaAripiprazole monotherapyBipolar maniaMixed episodesEffective therapyEffect therapyAripiprazoleAdditional weeksHaloperidolWeek 3PlaceboPatientsTotal scoreTherapyMania
2002
An Open Trial of Morning Light Therapy for Treatment of Antepartum Depression
Oren D, Wisner K, Spinelli M, Epperson C, Peindl K, Terman J, Terman M. An Open Trial of Morning Light Therapy for Treatment of Antepartum Depression. American Journal Of Psychiatry 2002, 159: 666-669. PMID: 11925310, DOI: 10.1176/appi.ajp.159.4.666.Peer-Reviewed Original ResearchConceptsWeeks of treatmentMorning light therapyBright light therapyLight therapyAntepartum depressionOpen trialMajor depressionMorning bright light therapyHamilton Depression Rating ScaleSeasonal Affective Disorder VersionDepression Rating ScaleNovel treatment approachesFollow-up questionnairePregnant patientsAntidepressant effectsPregnant womenDepression ratingsTreatment approachesTherapyRating ScaleAdverse effectsDepressionTrialsWeeksPregnancy
2000
No effect of light on basal glucagon levels in winter seasonal depressives and comparison subjects
Oren D, Berman R, Anand A, Charney D. No effect of light on basal glucagon levels in winter seasonal depressives and comparison subjects. Psychiatry Research 2000, 94: 263-266. PMID: 10889291, DOI: 10.1016/s0165-1781(00)00158-x.Peer-Reviewed Original Research
1999
Effect of catecholamine depletion on lithium-induced long-term remission of bipolar disorder
Anand A, Darnell A, Miller H, Berman R, Cappiello A, Oren D, Woods S, Charney D. Effect of catecholamine depletion on lithium-induced long-term remission of bipolar disorder. Biological Psychiatry 1999, 45: 972-978. PMID: 10386179, DOI: 10.1016/s0006-3223(98)00293-5.Peer-Reviewed Original ResearchConceptsLong-term remissionBipolar disorderCatecholamine depletionLithium therapyHypomanic symptomsLong-term lithium therapyRandomized double-blind mannerDSM-IV bipolar disorderDouble-blind mannerMechanism of preventionTransient relapseManic relapsePlacebo administrationSerum levelsCatecholamine systemsHomovanillic acidRemissionRelapseDisordersTherapyTest sessionsSymptomsSubjectsSignificant changesMood indices
1996
Circadian profiles of cortisol, prolactin, and thyrotropin in seasonal affective disorder
Oren D, Levendosky A, Kasper S, Duncan C, Rosenthal N. Circadian profiles of cortisol, prolactin, and thyrotropin in seasonal affective disorder. Biological Psychiatry 1996, 39: 157-170. PMID: 8837977, DOI: 10.1016/0006-3223(95)00079-8.Peer-Reviewed Original Research
1993
Effects of phototherapy on electrooculographic ratio in winter seasonal affective disorder
Ozaki N, Rosenthal N, Moul D, Schwartz P, Oren D. Effects of phototherapy on electrooculographic ratio in winter seasonal affective disorder. Psychiatry Research 1993, 49: 99-107. PMID: 8153191, DOI: 10.1016/0165-1781(93)90098-2.Peer-Reviewed Original ResearchConceptsSeasonal affective disorderControl subjectsLight therapyEOG ratiosSAD patientsAffective disordersEffect of phototherapyNormal control subjectsWinter seasonal affective disorderRetinal abnormalitiesPatientsConfounding factorsEOG testingTherapyDisordersSubjectsTest variabilityOutpatientsAbnormalitiesPhototherapySpontaneous eye blink rate in winter seasonal affective disorder
Barbato G, Moul D, Schwartz P, Rosenthal N, Oren D. Spontaneous eye blink rate in winter seasonal affective disorder. Psychiatry Research 1993, 47: 79-85. PMID: 8516420, DOI: 10.1016/0165-1781(93)90057-n.Peer-Reviewed Original ResearchConceptsSeasonal affective disorderNormal control subjectsSpontaneous eye blink rateWinter seasonal affective disorderEye blink rateControl subjectsLight therapyBlink rateAffective disordersPremenopausal female subjectsSAD patientsDrug-free patientsElevated blink ratePatientsBiological markersFemale subjectsSignificant decreaseSignificant differencesTherapyDisordersSignificant changesPossible linkSubjectsTreatmentExploratory analysisSide effects of light therapy in seasonal affective disorder
Levitt A, Joffe R, Moul D, Lam R, Teicher M, Lebegue B, Murray M, Oren D, Schwartz P, Buchanan A. Side effects of light therapy in seasonal affective disorder. American Journal Of Psychiatry 1993, 150: 650-652. PMID: 8465886, DOI: 10.1176/ajp.150.4.650.Peer-Reviewed Original ResearchLight visor treament for seasonal affective disorder: A multicenter study
Joffe R, Moul D, Lam R, Levitt A, Teicher M, Lebegue B, Oren D, Buchanan A, Glod C, Murray M, Brown J, Schwartz P. Light visor treament for seasonal affective disorder: A multicenter study. Psychiatry Research 1993, 46: 29-39. PMID: 8464953, DOI: 10.1016/0165-1781(93)90005-2.Peer-Reviewed Original ResearchConceptsSeasonal affective disorderAntidepressant responseLight therapyAffective disordersTreatment of SADSeverity of depressionAntidepressant actionAntidepressant efficacyMulticenter studyMedication statusNonspecific effectsSimilar frequencySignificant differencesTherapyParallel designDisordersTreatmentPrevious studies