2022
Comparison of Lanthanide Macrocyclic Complexes as 23Na NMR Sensors
Khan MH, Mishra SK, Zakaria ABM, Mihailović J, Coman D, Hyder F. Comparison of Lanthanide Macrocyclic Complexes as 23Na NMR Sensors. Analytical Chemistry 2022, 94: 2536-2545. PMID: 35073049, DOI: 10.1021/acs.analchem.1c04432.Peer-Reviewed Original ResearchConceptsLanthanide macrocyclic complexesParamagnetic lanthanide ionsMagnetic resonance agentsLanthanide complexesMacrocyclic complexesMacrocyclic designDownfield shiftLanthanide ionsNa NMRBulk magnetic susceptibility effectsUnpaired electronChelating agentBiomedical applicationsNegative chargeNMR sensorSodium ionsTriazacyclononaneIonsComplexesBiological importanceMacrocyclicTmDOTPNaCationsGd
2014
Characterization of a lanthanide complex encapsulated with MRI contrast agents into liposomes for biosensor imaging of redundant deviation in shifts (BIRDS)
Maritim S, Huang Y, Coman D, Hyder F. Characterization of a lanthanide complex encapsulated with MRI contrast agents into liposomes for biosensor imaging of redundant deviation in shifts (BIRDS). JBIC Journal Of Biological Inorganic Chemistry 2014, 19: 1385-1398. PMID: 25304046, PMCID: PMC4348029, DOI: 10.1007/s00775-014-1200-z.Peer-Reviewed Original ResearchMeSH KeywordsBiosensing TechniquesContrast MediaCoordination ComplexesLanthanoid Series ElementsLiposomesMagnetic Resonance ImagingMolecular ImagingMolecular StructureConceptsLanthanide complexesMagnetic resonance imaging (MRI) probesParamagnetic lanthanide complexesT2 contrast agentsRedundant deviationMolecular imagingMRI contrast agentsNon-exchangeable protonsContrast agentsMRI contrastChemical shiftsMRI probesLiposomal encapsulation efficiencyParamagnetic environmentSignal amplificationEncapsulation efficiencyWater relaxationProbe environmentTransverse relaxation timeParamagnetic effectImaging probeHigh spatial resolutionParamagnetic agentsParamagnetic contrast agentRelaxation timeLanthanide ion (III) complexes of 1,4,7,10‐tetraazacyclododecane‐1,4,7,10‐tetraaminophosphonate for dual biosensing of pH with chemical exchange saturation transfer (CEST) and biosensor imaging of redundant deviation in shifts (BIRDS)
Huang Y, Coman D, Ali MM, Hyder F. Lanthanide ion (III) complexes of 1,4,7,10‐tetraazacyclododecane‐1,4,7,10‐tetraaminophosphonate for dual biosensing of pH with chemical exchange saturation transfer (CEST) and biosensor imaging of redundant deviation in shifts (BIRDS). Contrast Media & Molecular Imaging 2014, 10: 51-58. PMID: 24801742, PMCID: PMC4222994, DOI: 10.1002/cmmi.1604.Peer-Reviewed Original ResearchMeSH KeywordsBiosensing TechniquesContrast MediaCyclamsDiagnostic ImagingGadoliniumHeterocyclic CompoundsHumansHydrogen-Ion ConcentrationLanthanoid Series ElementsThuliumYtterbiumConceptsChemical exchange saturation transferLanthanide complexesExchangeable protonsProton resonancesPH imagingLanthanide ion complexesRedundant deviationChemical shift differencesChemical exchange saturation transfer contrastCEST contrastIon complexesChemical shiftsQuantitative pH imagingShift differencesSingle-proton resonancesChemical shift imaging methodsMagnetic resonanceCEST experimentsWater protonsNonexchangeable protonsParamagnetic effectSaturation transferBiosensorComplexesWater resonance