2024
Automated detection of early signs of irreversible ischemic change on CTA source images in patients with large vessel occlusion
Mak A, Matouk C, Avery E, Behland J, Haider S, Frey D, Madai V, Vajkoczy P, Griessenauer C, Zand R, Hendrix P, Abedi V, Sanelli P, Falcone G, Petersen N, Sansing L, Sheth K, Payabvash S, Malhotra A. Automated detection of early signs of irreversible ischemic change on CTA source images in patients with large vessel occlusion. PLOS ONE 2024, 19: e0304962. PMID: 38870240, PMCID: PMC11175522, DOI: 10.1371/journal.pone.0304962.Peer-Reviewed Original ResearchConceptsDiffusion-weighted imagingLarge vessel occlusionIrreversible ischemic changesPoor functional outcomeFunctional outcomesIschemic changesInfarct volumeAlberta Stroke Program Early CT ScorePredicting poor functional outcomeVessel occlusionFollow-up diffusion-weighted imagingAnterior circulation LVO strokeCTA source imagesReceiver operating characteristic curveExpert human readersPredicting final infarctionASPECTS regionsAdmission CTANon-inferior performanceBaseline CTACT scoreFinal infarctEndovascular therapyHU attenuationValidation cohort
2023
The Impact of Dual Antiplatelet Therapy Duration on Unruptured Aneurysm Occlusion After Flow Diversion: A Multicenter Study
Vranic J, Harker P, Stapleton C, Regenhardt R, Dmytriw A, Doron O, Alotaibi N, Leslie-Mazwi T, Gupta R, Berglar I, Tan C, Koch M, Raymond S, Mascitelli J, Patterson T, Seinfeld J, White A, Case D, Roark C, Gandhi C, Al-Mufti F, Cooper J, Matouk C, Sujijantarat N, Devia D, Ocampo-Navia M, Villamizar-Torres D, Puentes J, Patel A. The Impact of Dual Antiplatelet Therapy Duration on Unruptured Aneurysm Occlusion After Flow Diversion: A Multicenter Study. Journal Of Computer Assisted Tomography 2023, 47: 753-758. PMID: 37707405, DOI: 10.1097/rct.0000000000001457.Peer-Reviewed Original ResearchMeSH KeywordsAspirinEmbolization, TherapeuticHumansIntracranial AneurysmPlatelet Aggregation InhibitorsRetrospective StudiesStentsTreatment OutcomeConceptsDual antiplatelet therapyAneurysm occlusion rateAneurysm occlusionDAPT durationThromboembolic complicationsOcclusion rateFlow diversionDuration of DAPTDual antiplatelet therapy durationIntracranial aneurysmsSingle Pipeline Embolization DeviceAntiplatelet therapy durationEndoluminal flow diversionRate of complicationsPrimary outcome measurePipeline Embolization DeviceSignificant differencesUnruptured intracranial aneurysmsAspirin monotherapyAntiplatelet therapyIschemic strokeTherapy durationIatrogenic complicationsRetrospective reviewMulticenter studyPredictors of Angiographic Outcome After Failed Thrombectomy for Large Vessel Occlusion: Insights from the Stroke Thrombectomy and Aneurysm Registry
Webb M, Essibayi M, Al Kasab S, Maier I, Psychogios M, Grossberg J, Alawieh A, Wolfe S, Arthur A, Dumont T, Kan P, Kim J, De Leacy R, Osbun J, Rai A, Jabbour P, Park M, Crosa R, Levitt M, Polifka A, Yoshimura S, Matouk C, Williamson R, Fragata I, Chowdhry S, Starke R, Samaniego E, Cuellar H, Spiotta A, Mascitelli J. Predictors of Angiographic Outcome After Failed Thrombectomy for Large Vessel Occlusion: Insights from the Stroke Thrombectomy and Aneurysm Registry. Neurosurgery 2023, 93: 1168-1179. PMID: 37377425, DOI: 10.1227/neu.0000000000002560.Peer-Reviewed Original ResearchMeSH KeywordsAneurysmBrain IschemiaCerebral HemorrhageHumansRegistriesRetrospective StudiesStrokeThrombectomyTreatment OutcomeConceptsLarge vessel occlusionMechanical thrombectomyProcedure timeSubgroup analysisPosterior circulation large vessel occlusionOnset-to-puncture timeAssociated with more complicationsStroke thrombectomyVessel occlusionPremorbid modified Rankin ScaleAneurysm RegistrySymptomatic intracerebral hemorrhageIncreased procedure timeBalloon guide catheterInternal carotid arteryAssociated with lesser oddsRescue intracranial stentingPredictors of angiographic outcomeRescue stentingRetrospective reviewM2 occlusionsAngiographic outcomesNo significant differenceFailed thrombectomyIntracerebral hemorrhageHigher Hospital Frailty Risk Score Is Associated With Increased Risk of Stroke: Observational and Genetic Analyses
Renedo D, Acosta J, Koo A, Rivier C, Sujijantarat N, de Havenon A, Sharma R, Gill T, Sheth K, Falcone G, Matouk C. Higher Hospital Frailty Risk Score Is Associated With Increased Risk of Stroke: Observational and Genetic Analyses. Stroke 2023, 54: 1538-1547. PMID: 37216451, PMCID: PMC10212531, DOI: 10.1161/strokeaha.122.041891.Peer-Reviewed Original ResearchMeSH KeywordsHemorrhagic StrokeHospitalsHumansPopulation HealthRetrospective StudiesRisk FactorsStrokeConceptsHospital Frailty Risk ScoreRisk of strokeHighest Hospital Frailty Risk ScoresDate of consentFrailty Risk ScoreMendelian randomization analysisStroke riskRisk scoreRandomization analysisTime of enrollmentAvailable electronic health recordsMendelian randomizationElectronic health recordsLook-back periodIncident strokeDose-response wayFrailty statusHemorrhagic strokeMultivariable analysisStroke eventsObservational studyHigh riskFrailtySignificant associationSimilar associationEmergent external ventricular drain placement in patients with factor Xa inhibitor-associated intracerebral hemorrhage after reversal with andexanet alfa
Ammar A, Elsamadicy A, Ammar M, Reeves B, Koo A, Falcone G, Hwang D, Petersen N, Kim J, Beekman R, Prust M, Magid-Bernstein J, Acosta J, Herbert R, Sheth K, Matouk C, Gilmore E. Emergent external ventricular drain placement in patients with factor Xa inhibitor-associated intracerebral hemorrhage after reversal with andexanet alfa. Clinical Neurology And Neurosurgery 2023, 226: 107621. PMID: 36791588, DOI: 10.1016/j.clineuro.2023.107621.Peer-Reviewed Original ResearchMeSH KeywordsAdultCerebral HemorrhageDrainageFactor XaFactor Xa InhibitorsFibrinolytic AgentsHumansProspective StudiesRecombinant ProteinsRetrospective StudiesThrombosisConceptsAndexanet alfaExtra-axial hemorrhageEVD placementThrombotic eventsNew hemorrhagePrimary safety outcomeExternal ventricular drain placementLarge prospective studiesIntensive care unitIntracerebral hemorrhage patientsVentricular drain placementBolus patientsHospital lengthHospital LOSICU LOSTract hemorrhageRankin scoreSecondary outcomesAdult patientsBolus groupPrimary outcomeCare unitIntracerebral hemorrhageLong administration timeHemorrhage patients
2018
Risk of Branch Occlusion and Ischemic Complications with the Pipeline Embolization Device in the Treatment of Posterior Circulation Aneurysms
Adeeb N, Griessenauer C, Dmytriw A, Shallwani H, Gupta R, Foreman P, Shakir H, Moore J, Limbucci N, Mangiafico S, Kumar A, Michelozzi C, Zhang Y, Pereira V, Matouk C, Harrigan M, Siddiqui A, Levy E, Renieri L, Marotta T, Cognard C, Ogilvy C, Thomas A. Risk of Branch Occlusion and Ischemic Complications with the Pipeline Embolization Device in the Treatment of Posterior Circulation Aneurysms. American Journal Of Neuroradiology 2018, 39: 1303-1309. PMID: 29880475, PMCID: PMC7655425, DOI: 10.3174/ajnr.a5696.Peer-Reviewed Original ResearchConceptsPosterior circulation aneurysmsPipeline Embolization DevicePosterior cerebral arteryIschemic complicationsInferior cerebellar arteryEmbolization DeviceVertebral arteryCerebellar arteryCerebral arteryBranch occlusionAnterior inferior cerebellar arteryPosterior inferior cerebellar arteryCohort of patientsContralateral vertebral arteryLow associated morbiditySuperior cerebellar arteryLong-term patencyAnterior circulationIschemic eventsAssociated morbidityConsecutive patientsPosterior circulationEndovascular treatmentMultivariable analysisRetrospective review
2012
Carotid Artery Angioplasty and Stenting for Patients Less than 70 Years-of-Age
Alkins R, Matouk CC, Cruz JP, Marotta T, Montanera W, Spears J. Carotid Artery Angioplasty and Stenting for Patients Less than 70 Years-of-Age. Canadian Journal Of Neurological Sciences / Journal Canadien Des Sciences Neurologiques 2012, 39: 338-342. PMID: 22547514, DOI: 10.1017/s0317167100013470.Peer-Reviewed Original ResearchConceptsDeath/stroke/myocardial infarctionStroke/myocardial infarctionCarotid artery angioplastyMyocardial infarctionYears of ageCarotid endarterectomyArtery angioplastyComposite outcomeAverage-risk patientsAdverse event ratesSimilar complication ratesAcute myocardial infarctionLongitudinal cohort studySt. Michael's HospitalComposite deathCohort studyRisk patientsComplication rateConsecutive patientsMajor complicationsPatient ageConsecutive seriesCAS proceduresOutcome measuresStroke rate