2024
Deep learning for prediction of post-thrombectomy outcomes based on admission CT angiography in large vessel occlusion stroke
Sommer J, Dierksen F, Zeevi T, Tran A, Avery E, Mak A, Malhotra A, Matouk C, Falcone G, Torres-Lopez V, Aneja S, Duncan J, Sansing L, Sheth K, Payabvash S. Deep learning for prediction of post-thrombectomy outcomes based on admission CT angiography in large vessel occlusion stroke. Frontiers In Artificial Intelligence 2024, 7: 1369702. PMID: 39149161, PMCID: PMC11324606, DOI: 10.3389/frai.2024.1369702.Peer-Reviewed Original ResearchEnd-to-endComputed tomography angiographyLarge vessel occlusionConvolutional neural networkDeep learning pipelineTrain separate modelsLogistic regression modelsResNet-50Deep learningAdmission computed tomography angiographyNeural networkLearning pipelineAdmission CT angiographyPreprocessing stepDiagnosis of large vessel occlusionsLarge vessel occlusion strokeReceiver operating characteristic areaEnsemble modelAutomated modelPre-existing morbidityCT angiographyReperfusion successNeurological examCross-validationOcclusion strokeAutomated detection of early signs of irreversible ischemic change on CTA source images in patients with large vessel occlusion
Mak A, Matouk C, Avery E, Behland J, Haider S, Frey D, Madai V, Vajkoczy P, Griessenauer C, Zand R, Hendrix P, Abedi V, Sanelli P, Falcone G, Petersen N, Sansing L, Sheth K, Payabvash S, Malhotra A. Automated detection of early signs of irreversible ischemic change on CTA source images in patients with large vessel occlusion. PLOS ONE 2024, 19: e0304962. PMID: 38870240, PMCID: PMC11175522, DOI: 10.1371/journal.pone.0304962.Peer-Reviewed Original ResearchConceptsDiffusion-weighted imagingLarge vessel occlusionIrreversible ischemic changesPoor functional outcomeFunctional outcomesIschemic changesInfarct volumeAlberta Stroke Program Early CT ScorePredicting poor functional outcomeVessel occlusionFollow-up diffusion-weighted imagingAnterior circulation LVO strokeCTA source imagesReceiver operating characteristic curveExpert human readersPredicting final infarctionASPECTS regionsAdmission CTANon-inferior performanceBaseline CTACT scoreFinal infarctEndovascular therapyHU attenuationValidation cohortOutcomes of Mechanical Thrombectomy for Patients With Stroke Presenting With Low Alberta Stroke Program Early Computed Tomography Score in Early and Late Time Windows
Elawady S, Cunningham C, Matsukawa H, Uchida K, Lin S, Maier I, Jabbour P, Kim J, Wolfe S, Rai A, Starke R, Psychogios M, Samaniego E, Arthur A, Yoshimura S, Cuellar H, Grossberg J, Alawieh A, Romano D, Tanweer O, Mascitelli J, Fragata I, Polifka A, Osbun J, Crosa R, Matouk C, Park M, Levitt M, Brinjikji W, Moss M, Dumont T, Williamson R, Navia P, Kan P, De Leacy R, Chowdhry S, Ezzeldin M, Spiotta A, Al Kasab S. Outcomes of Mechanical Thrombectomy for Patients With Stroke Presenting With Low Alberta Stroke Program Early Computed Tomography Score in Early and Late Time Windows. Neurosurgery 2024, 95: 877-885. PMID: 38758725, DOI: 10.1227/neu.0000000000002992.Peer-Reviewed Original ResearchAlberta Stroke Program Early Computed Tomography ScoreLower Alberta Stroke Program Early Computed Tomography ScoreComputed Tomography ScoreLarge vessel occlusionMechanical thrombectomyRate of symptomatic ICHMedian admission National Institutes of Health Stroke Scale scoreAnterior circulation large vessel occlusionProportion of female patientsVessel occlusionPrevalence of atrial fibrillationIntracranial large vessel occlusionAdmission National Institutes of Health Stroke Scale scoreNational Institutes of Health Stroke Scale scoreMulticenter international registryOutcomes of mechanical thrombectomyRetrospective cohort studyWindow groupStroke Scale scoreSymptomatic ICHNo significant differenceFemale patientsPropensity matchingAtrial fibrillationInternational registryRadiomics-Based Prediction of Collateral Status from CT Angiography of Patients Following a Large Vessel Occlusion Stroke
Avery E, Abou-Karam A, Abi-Fadel S, Behland J, Mak A, Haider S, Zeevi T, Sanelli P, Filippi C, Malhotra A, Matouk C, Falcone G, Petersen N, Sansing L, Sheth K, Payabvash S. Radiomics-Based Prediction of Collateral Status from CT Angiography of Patients Following a Large Vessel Occlusion Stroke. Diagnostics 2024, 14: 485. PMID: 38472957, PMCID: PMC10930945, DOI: 10.3390/diagnostics14050485.Peer-Reviewed Original ResearchCollateral statusCollateral scoreLarge vessel occlusionAcute LVO strokeRadiomics modelTest cohortCT angiography of patientsAdmission computed tomography angiographyAnterior circulation territoryAngiography of patientsLong-term outcomesReceiver operating characteristic areaRadiomics-based predictionCollateral arterial circulationOperating characteristics areaAdmission CTACirculation territoryCT angiographyClinical outcomesRadiomic featuresTreatment triageOcclusion strokeVessel occlusionPatientsArterial circulation
2023
Predictors of Angiographic Outcome After Failed Thrombectomy for Large Vessel Occlusion: Insights from the Stroke Thrombectomy and Aneurysm Registry
Webb M, Essibayi M, Al Kasab S, Maier I, Psychogios M, Grossberg J, Alawieh A, Wolfe S, Arthur A, Dumont T, Kan P, Kim J, De Leacy R, Osbun J, Rai A, Jabbour P, Park M, Crosa R, Levitt M, Polifka A, Yoshimura S, Matouk C, Williamson R, Fragata I, Chowdhry S, Starke R, Samaniego E, Cuellar H, Spiotta A, Mascitelli J. Predictors of Angiographic Outcome After Failed Thrombectomy for Large Vessel Occlusion: Insights from the Stroke Thrombectomy and Aneurysm Registry. Neurosurgery 2023, 93: 1168-1179. PMID: 37377425, DOI: 10.1227/neu.0000000000002560.Peer-Reviewed Original ResearchConceptsLarge vessel occlusionMechanical thrombectomyProcedure timeSubgroup analysisPosterior circulation large vessel occlusionOnset-to-puncture timeAssociated with more complicationsStroke thrombectomyVessel occlusionPremorbid modified Rankin ScaleAneurysm RegistrySymptomatic intracerebral hemorrhageIncreased procedure timeBalloon guide catheterInternal carotid arteryAssociated with lesser oddsRescue intracranial stentingPredictors of angiographic outcomeRescue stentingRetrospective reviewM2 occlusionsAngiographic outcomesNo significant differenceFailed thrombectomyIntracerebral hemorrhage