2020
Cytomorphologic features of thyroid disease in patients with DICER1 mutations: A report of cytology–histopathology correlation in 7 patients
Darbinyan A, Morotti R, Cai G, Prasad ML, Christison‐Lagay E, Dinauer C, Adeniran AJ. Cytomorphologic features of thyroid disease in patients with DICER1 mutations: A report of cytology–histopathology correlation in 7 patients. Cancer Cytopathology 2020, 128: 746-756. PMID: 32897650, DOI: 10.1002/cncy.22329.Peer-Reviewed Original ResearchConceptsDICER1 mutationsThyroid diseaseThyroid carcinomaScreening of patientsFine-needle aspiration samplesMonitoring of patientsDiagnostic cytologic featuresPapillary thyroid carcinomaGermline DICER1 mutationsThyroid fine-needle aspiration samplesFNA evaluationUndetermined significanceDifferent somatic variantsThyroid cancerScant colloidNeoplastic lesionsHistopathological analysisCytomorphologic featuresDICER1 syndromeModerate cellularityCytologic featuresFollicular carcinomaFollicular lesionsInconspicuous nucleoliFollicular neoplasmRecurrence and Complications in Pediatric and Adolescent Papillary Thyroid Cancer in a High-Volume Practice
Rubinstein JC, Herrick-Reynolds K, Dinauer C, Morotti R, Solomon D, Callender GG, Christison-Lagay ER. Recurrence and Complications in Pediatric and Adolescent Papillary Thyroid Cancer in a High-Volume Practice. Journal Of Surgical Research 2020, 249: 58-66. PMID: 31923715, DOI: 10.1016/j.jss.2019.12.002.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAge FactorsChildFemaleFollow-Up StudiesHospitals, High-VolumeHumansLymph NodesLymphatic MetastasisMaleNeoplasm Recurrence, LocalPostoperative ComplicationsPrognosisRetrospective StudiesRisk AssessmentRisk FactorsSurvival AnalysisThyroid Cancer, PapillaryThyroid GlandThyroid NeoplasmsThyroidectomyTreatment OutcomeYoung AdultConceptsPediatric papillary thyroid cancerLateral neck diseaseNeck diseasePapillary thyroid cancerNode involvementThyroid cancerExact testLymph node involvementCentral neck dissectionExtent of diseasePredictors of recurrenceRetrospective case seriesNon-Caucasian raceCox proportional hazardsLateral node involvementHigh-volume practiceFisher's exact testDisease recurrenceLymphovascular invasionMedian ageNeck dissectionCase seriesIndependent predictorsRetrospective reviewTumor size
2017
Pathologic Characteristics, Natural History, and Prognostic Implications of BRAFV600E Mutation in Pediatric Papillary Thyroid Carcinoma
Hardee S, Prasad ML, Hui P, Dinauer CA, Morotti RA. Pathologic Characteristics, Natural History, and Prognostic Implications of BRAFV600E Mutation in Pediatric Papillary Thyroid Carcinoma. Pediatric And Developmental Pathology 2017, 20: 206-212. PMID: 28521635, DOI: 10.1177/1093526616689628.Peer-Reviewed Original ResearchConceptsPapillary thyroid cancerPediatric papillary thyroid cancerPrognostic implicationsPediatric papillary thyroid carcinomaNegative casesBRAF-negative casesBRAF-negative patientsBRAF-positive casesTertiary medical centerAggressive clinical coursePapillary thyroid carcinomaSurgical pathology diagnosisCommon genetic aberrationsNegative patientsAggressive courseClinical coursePathologic characteristicsCase seriesClinical outcomesRetrospective reviewAggressive featuresPediatric casesRecurrence rateRetrospective studySingle institution
2007
Thyroid Cancer in Children
Dinauer C, Francis GL. Thyroid Cancer in Children. Endocrinology And Metabolism Clinics Of North America 2007, 36: 779-806. PMID: 17673128, DOI: 10.1016/j.ecl.2007.04.002.ChaptersConceptsDetectable serum thyroglobulinThyroid cancerSerum thyroglobulinNegative whole-body scanNegative imaging studiesManagement of childrenChildhood thyroid cancerRobust immune responseWhole-body scanYears of ageHigh-risk categoryGrowth factor expression patternsRecurrent diseaseUncommon tumorCurrent guidelinesImmune responseHigh riskImaging studiesCancerUnique subsetGenetic mutationsLimited dataChildrenPatientsThyroglobulin
2003
Treatment of Recurrent Papillary Thyroid Carcinoma in Children and Adolescents
Powers PA, Dinauer CA, Tuttle RM, Francis GL. Treatment of Recurrent Papillary Thyroid Carcinoma in Children and Adolescents. Journal Of Pediatric Endocrinology And Metabolism 2003, 16: 1033-1040. PMID: 14513881, DOI: 10.1515/jpem.2003.16.7.1033.Peer-Reviewed Original ResearchConceptsRecurrent papillary thyroid carcinomaPapillary thyroid carcinomaThyroid carcinomaYears of ageThird remissionCervical nodesPersistent diseaseClinical coursePoor prognosisSecond recurrenceHigh mortalityRemissionChildrenCarcinomaRecurrenceMortalityTreatmentAdultsPrevious dataPatientsPrognosisDisease