2024
Molecular Genetics Augment Cytopathologic Evaluation and Surgical Planning of Pediatric Thyroid Nodules
Spaulding S, Maayah M, Dinauer C, Prasad M, Darbinyan A, Morotti R, Christison-Lagay E. Molecular Genetics Augment Cytopathologic Evaluation and Surgical Planning of Pediatric Thyroid Nodules. Journal Of Pediatric Surgery 2024, 59: 975-980. PMID: 38246817, DOI: 10.1016/j.jpedsurg.2024.01.001.Peer-Reviewed Original ResearchFine-needle aspiration biopsyPediatric thyroid nodulesMolecular genetic testingBethesda IV nodulesPrediction of malignancyDICER1 mutationsThyroid nodulesGenetic testingNRAS mutationsMethods Retrospective chart reviewRetrospective chart reviewTime of surgeryBRAF V600E testingMutations/fusionsBethesda III nodulesChart reviewSurgical resectionFinal histopathologyThyroid resectionPediatric dataHistologic classificationSurgical specimensBRAF mutationsAspiration biopsyCytopathologic evaluation
2022
Differences in the management of thyroid nodules in children and adolescents as compared to adults
Goldfarb M, Dinauer C. Differences in the management of thyroid nodules in children and adolescents as compared to adults. Current Opinion In Endocrinology Diabetes And Obesity 2022, 29: 466-473. PMID: 35777975, DOI: 10.1097/med.0000000000000754.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsPediatric thyroid nodulesThyroid nodulesFine-needle aspiration biopsyRisk of malignancyRisk stratification systemSpecific risk factorsAppropriate imaging modalityNeedle aspiration biopsyCertain genetic syndromesYounger patientsNonoperative approachClinical managementRadiofrequency ablationRisk factorsPretest probabilityAspiration biopsyMiRNA classifierSpecific molecular testsMolecular testingUltrasound characteristicsAge groupsGenetic syndromesClinical usePatientsBenign nodules