Making Drug Approval Decisions in the Face of Uncertainty: Cumulative Evidence versus Value of Information
Dijk S, Krijkamp E, Kunst N, Labrecque J, Gross C, Pandit A, Lu C, Visser L, Wong J, Hunink M. Making Drug Approval Decisions in the Face of Uncertainty: Cumulative Evidence versus Value of Information. Medical Decision Making 2024, 44: 512-528. PMID: 38828516, PMCID: PMC11283736, DOI: 10.1177/0272989x241255047.Peer-Reviewed Original ResearchValue-of-informationVOI approachPolicy decisionsValue-of-information analysisSuboptimal resource useEvidence accumulationVOI resultsAdministrative policy decisionsDecision making resultsDecision-making strategiesApproval decisionsPolicy approachesMeta-analysisResearch settingsResource useHealth technology assessmentCrisis responseCase studyPolicyCumulative evidenceResource allocationComplexity of decisionsResearch prioritizationDecisionHealth outcomesFunctional decline in older breast cancer survivors treated with and without chemotherapy and non-cancer controls: results from the Hurria Older PatiEnts (HOPE) prospective study
Sedrak M, Sun C, Bae M, Freedman R, Magnuson A, O’Connor T, Moy B, Wildes T, Klepin H, Chapman A, Tew W, Dotan E, Fenton M, Kim H, Katheria V, Muss H, Cohen H, Gross C, Ji J. Functional decline in older breast cancer survivors treated with and without chemotherapy and non-cancer controls: results from the Hurria Older PatiEnts (HOPE) prospective study. Journal Of Cancer Survivorship 2024, 18: 1131-1143. PMID: 38678525, PMCID: PMC11324395, DOI: 10.1007/s11764-024-01594-3.Peer-Reviewed Original ResearchEarly-stage breast cancerPF-10 scorePF-10Physical functionNon-cancer controlsFunctional declineBC controlOlder breast cancer survivorsRAND 36-Item Short FormBreast cancerCohort of older adultsOlder womenBreast cancer survivorsImprove health outcomesPhysical function subscalePhysical function declineAccelerated functional declineBreast Cancer StudyCancer survivorsFunction subscaleHealth outcomesGroup of womenOlder adultsControl groupShort form