2016
Tissue-Engineered Vascular Rings from Human iPSC-Derived Smooth Muscle Cells
Dash BC, Levi K, Schwan J, Luo J, Bartulos O, Wu H, Qiu C, Yi T, Ren Y, Campbell S, Rolle MW, Qyang Y. Tissue-Engineered Vascular Rings from Human iPSC-Derived Smooth Muscle Cells. Stem Cell Reports 2016, 7: 19-28. PMID: 27411102, PMCID: PMC4945325, DOI: 10.1016/j.stemcr.2016.05.004.Peer-Reviewed Original ResearchMeSH KeywordsCell DifferentiationCells, CulturedHumansInduced Pluripotent Stem CellsMuscle, Smooth, VascularMyocytes, Smooth MusclePhenotypeTissue EngineeringConceptsVascular tissue engineeringFunctional vascular smooth muscle cellsCell-based tissueSelf-assembly approachRenewable sourcesTissue engineeringPluripotent stem cellsPlatform technologyBiomedical applicationsTissue ringsDrug screeningDisease modelingTissue model systemsHuman iPSCStem cellsBroad utilityEfficient approachLarge quantitiesEngineeringMaterials
2013
Small-Diameter Vascular Graft Engineered Using Human Embryonic Stem Cell-Derived Mesenchymal Cells
Sundaram S, Echter A, Sivarapatna A, Qiu C, Niklason L. Small-Diameter Vascular Graft Engineered Using Human Embryonic Stem Cell-Derived Mesenchymal Cells. Tissue Engineering Part A 2013, 20: 740-750. PMID: 24125588, PMCID: PMC3926168, DOI: 10.1089/ten.tea.2012.0738.Peer-Reviewed Original ResearchConceptsHuman embryonic stem cellsHuman embryonic stem cell-derived mesenchymal cellsSmooth muscle cellsSMC marker expressionMesenchymal cellsEmbryonic stem cellsMarkers of cartilageLineage commitmentNew cell sourceGrowth factor betaStem cellsDifferentiation capabilityCell populationsNative counterpartsMuscle cellsHuman vessel wallStringent analysisFactor betaCell sourceCellsMarker expressionSmooth muscle actinMuscle actinVascular constructsCell sourcing