Featured Publications
Survival of the Fittest: Impact of Cardiorespiratory Fitness on Outcomes in Men and Women with Cardiovascular Disease
Safdar B, Mangi AA. Survival of the Fittest: Impact of Cardiorespiratory Fitness on Outcomes in Men and Women with Cardiovascular Disease. Clinical Therapeutics 2020, 42: 385-392. PMID: 32088022, DOI: 10.1016/j.clinthera.2020.01.014.Peer-Reviewed Original ResearchMeSH KeywordsCardiorespiratory FitnessCardiovascular DiseasesExercise TherapyFemaleHumansMaleRisk FactorsSex FactorsConceptsPeak cardiorespiratory fitnessCardiorespiratory fitnessCardiovascular diseaseCardiac rehabilitationPhysical inactivityMyocardial infarctionImpact of CRFOnset of CVDPeak exercise capacityCardiac rehabilitation programModifiable risk factorsRecurrent myocardial infarctionPoor functional outcomeCause of mortalitySex differencesImpact of sexCVD outcomesExercise capacityImproved survivalLow referralMale patientsFemale patientsExercise prescriptionFunctional outcomeRisk factors
2023
Appraising the Preclinical Evidence of the Role of the Renin-Angiotensin-Aldosterone System in Antenatal Programming of Maternal and Offspring Cardiovascular Health Across the Life Course: Moving the Field Forward: A Scientific Statement From the American Heart Association
Alexander B, South A, August P, Bertagnolli M, Ferranti E, Grobe J, Jones E, Loria A, Safdar B, Sequeira-Lopez M, Health O. Appraising the Preclinical Evidence of the Role of the Renin-Angiotensin-Aldosterone System in Antenatal Programming of Maternal and Offspring Cardiovascular Health Across the Life Course: Moving the Field Forward: A Scientific Statement From the American Heart Association. Hypertension 2023, 80: e75-e89. PMID: 36951054, PMCID: PMC10242542, DOI: 10.1161/hyp.0000000000000227.Peer-Reviewed Original ResearchMeSH KeywordsAldosteroneAmerican Heart AssociationCardiovascular DiseasesFemaleHumansHypertensionMothersPlacentaPre-EclampsiaPregnancyReninRenin-Angiotensin SystemConceptsAldosterone systemCardiovascular healthCardiovascular diseaseLong-term cardiovascular healthAntenatal risk factorsRisk of hypertensionAdverse cardiovascular healthAmerican Heart AssociationMaternal-fetal healthTranslational research studiesPregnancy complicationsRenin-AngiotensinPreclinical evidenceComplicated pregnanciesPlacental interfaceHeart AssociationRisk factorsSystem dysregulationNovel therapiesClinical careRisk individualsHealth outcomesLife courseDiseaseScientific evidence
2021
Influence of Sex and Gender on Lifestyle Interventions for Cardiovascular Disease
Safdar B. Influence of Sex and Gender on Lifestyle Interventions for Cardiovascular Disease. Clinical Therapeutics 2021, 44: 8-10. PMID: 34973826, DOI: 10.1016/j.clinthera.2021.12.004.Peer-Reviewed Original Research