Biomarkers of Affective Dysregulation Associated with In Utero Exposure to EtOH
Darbinian N, Merabova N, Tatevosian G, Morrison M, Darbinyan A, Zhao H, Goetzl L, Selzer M. Biomarkers of Affective Dysregulation Associated with In Utero Exposure to EtOH. Cells 2023, 13: 2. PMID: 38201206, PMCID: PMC10778368, DOI: 10.3390/cells13010002.Peer-Reviewed Original ResearchConceptsSelective serotonin reuptake inhibitorsBrain-derived neurotrophic factorSerotonin transporter proteinEnzyme-linked immunosorbent assayEtOH exposureBDNF levelsGestational ageMaternal useSignificant upregulationFetal brainAffective dysregulationUnexposed controlsBrain monoamine pathwaysBrain-derived exosomesSerotonin reuptake inhibitorsFetal neural developmentWeeks of pregnancySERT protein levelsQuantitative reverse transcription polymerase chain reactionFetal brain samplesReverse transcription-polymerase chain reactionCaspase-3Fetal brain tissueTranscription-polymerase chain reactionDA transporter gene