2024
Prior Influenza Infection Mitigates SARS-CoV-2 Disease in Syrian Hamsters
Di Pietro C, Haberman A, Lindenbach B, Smith P, Bruscia E, Allore H, Vander Wyk B, Tyagi A, Zeiss C. Prior Influenza Infection Mitigates SARS-CoV-2 Disease in Syrian Hamsters. Viruses 2024, 16: 246. PMID: 38400021, PMCID: PMC10891789, DOI: 10.3390/v16020246.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCOVID-19CricetinaeDisease Models, AnimalHumansInfluenza A Virus, H1N1 SubtypeInfluenza, HumanLungMesocricetusSARS-CoV-2ConceptsTransient gene expressionSARS-CoV-2Viral replication pathwayReplication pathwayAntiviral pathwaysEndemism patternsUpregulation of innateGene expressionQuantitative RT-PCRMitigated weight lossDual-infected animalsSARS-CoV-2 viral loadSARS-CoV-2 infectionSyrian hamstersSeasonal infection ratesSARS-CoV-2 inoculationLungs of animalsIndividual virusesSARS-CoV-2 diseaseUpper respiratory tractH1N1 infectionRT-PCRBronchoalveolar lavageViral loadCytokine levels
2019
In vivo dynamics of T cells and their interactions with dendritic cells in mouse cutaneous graft-versus-host disease
Morin-Zorman S, Wysocki C, Zhu J, Li H, Zorman S, Matte-Martone C, Kisanga E, McNiff J, Jain D, Gonzalez D, Rothstein DM, Lakkis FG, Haberman A, Shlomchik WD. In vivo dynamics of T cells and their interactions with dendritic cells in mouse cutaneous graft-versus-host disease. Blood Advances 2019, 3: 2082-2092. PMID: 31296496, PMCID: PMC6650737, DOI: 10.1182/bloodadvances.2019000227.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBiomarkersCD11c AntigenCell CommunicationDendritic CellsDisease Models, AnimalFluorescent Antibody TechniqueGene ExpressionGenes, ReporterGraft vs Host DiseaseHematopoietic Stem Cell TransplantationHistocompatibility Antigens Class IImmunophenotypingLymphocyte DepletionMiceMice, TransgenicProtein BindingReceptors, Antigen, T-CellSkin DiseasesT-Lymphocyte SubsetsT-LymphocytesTransplantation, HomologousConceptsDonor dendritic cellsCD8 cellsT cellsGVHD lesionsHost diseaseCD4 cellsDendritic cellsAllogeneic hematopoietic stem cell transplantationHematopoietic stem cell transplantationMajority of CD4Dynamics of CD4Stem cell transplantationCutaneous graftAntibody infusionCell transplantationMyeloid cellsIntravital microscopyAcute deletionMajor causeLesionsTarget tissuesCD103CD4InfusionMHCII
2003
Rheumatoid Factors in Health and Disease: Structure, Function, Induction and Regulation
Haberman AM, William J, Euler C, Shlomchik MJ. Rheumatoid Factors in Health and Disease: Structure, Function, Induction and Regulation. Current Directions In Autoimmunity 2003, 6: 169-195. PMID: 12408052, DOI: 10.1159/000066861.Peer-Reviewed Original ResearchAnimalsAntibodies, Anti-IdiotypicAntigens, T-IndependentApoptosisAutoimmune DiseasesB-Lymphocyte SubsetsDisease Models, AnimalFas ReceptorHumansImmune ToleranceImmunizationImmunoglobulin Constant RegionsImmunoglobulin GLupus Erythematosus, SystemicMiceMice, Inbred MRL lprMice, TransgenicReference ValuesRheumatoid FactorT-Lymphocyte Subsets
1999
A Novel Mouse with B Cells but Lacking Serum Antibody Reveals an Antibody-independent Role for B Cells in Murine Lupus
Chan O, Hannum L, Haberman A, Madaio M, Shlomchik M. A Novel Mouse with B Cells but Lacking Serum Antibody Reveals an Antibody-independent Role for B Cells in Murine Lupus. Journal Of Experimental Medicine 1999, 189: 1639-1648. PMID: 10330443, PMCID: PMC2193634, DOI: 10.1084/jem.189.10.1639.Peer-Reviewed Original ResearchConceptsB cellsAutoantibody productionMRL/MpJ-Faslpr miceAutoreactive T cellsAntigen-presenting cellsAntibody-independent roleB cell functionFunctional B cellsExpression of diseaseSerum autoantibodiesMurine lupusLocal inflammationSystemic autoimmunitySerum antibodiesPathogenic roleAntigen presentationT cellsCellular infiltrationSurface immunoglobulinPathologic phenotypeDisease expressionCell functionMiceNovel mousePrecise role