2023
Super-enhancer hijacking drives ectopic expression of hedgehog pathway ligands in meningiomas
Youngblood M, Erson-Omay Z, Li C, Najem H, Coșkun S, Tyrtova E, Montejo J, Miyagishima D, Barak T, Nishimura S, Harmancı A, Clark V, Duran D, Huttner A, Avşar T, Bayri Y, Schramm J, Boetto J, Peyre M, Riche M, Goldbrunner R, Amankulor N, Louvi A, Bilgüvar K, Pamir M, Özduman K, Kilic T, Knight J, Simon M, Horbinski C, Kalamarides M, Timmer M, Heimberger A, Mishra-Gorur K, Moliterno J, Yasuno K, Günel M. Super-enhancer hijacking drives ectopic expression of hedgehog pathway ligands in meningiomas. Nature Communications 2023, 14: 6279. PMID: 37805627, PMCID: PMC10560290, DOI: 10.1038/s41467-023-41926-y.Peer-Reviewed Original Research
2011
Cilia in the CNS: The Quiet Organelle Claims Center Stage
Louvi A, Grove EA. Cilia in the CNS: The Quiet Organelle Claims Center Stage. Neuron 2011, 69: 1046-1060. PMID: 21435552, PMCID: PMC3070490, DOI: 10.1016/j.neuron.2011.03.002.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCentral Nervous SystemCiliaHedgehog ProteinsHumansNeurogenesisSignal TransductionConceptsPrimary ciliaSonic hedgehog (Shh) signal transductionHedgehog signal transductionHuman disease syndromesProtein traffickingBrain tumor formationSignal transductionCellular organellesGenetic disruptionSpecialized modeNeuronal signalingCiliaTumor formationAdult CNSAdult neurogenesisEukaryotesVertebratesOrganellesTransductionTraffickingSignalingBiologyDisease syndromeMajor linesNeurogenesis