2015
Predictors of Circulating Insulin-Like Growth Factor-1 and Insulin-Like Growth Factor–Binding Protein-3 in Critical Illness*
Ahasic AM, Tejera P, Wei Y, Su L, Mantzoros CS, Bajwa EK, Thompson BT, Christiani DC. Predictors of Circulating Insulin-Like Growth Factor-1 and Insulin-Like Growth Factor–Binding Protein-3 in Critical Illness*. Critical Care Medicine 2015, 43: 2651-2659. PMID: 26427594, PMCID: PMC4651824, DOI: 10.1097/ccm.0000000000001314.Peer-Reviewed Original ResearchMeSH KeywordsAcademic Medical CentersAcute DiseaseAge FactorsAgedAged, 80 and overAPACHEBody Mass IndexChronic DiseaseCritical IllnessFemaleGenotypeHumansInsulin-Like Growth Factor Binding Protein 3Insulin-Like Growth Factor IIntensive Care UnitsLinear ModelsMaleMiddle AgedPhenotypePolymorphism, GeneticProspective StudiesRisk FactorsSex FactorsConceptsInsulin-like growth factor-binding protein-3Insulin-like growth factor-1Acute respiratory distress syndromeGrowth factor-1Respiratory distress syndromeInsulin-like growth factor-binding protein-3 levelsProtein-3 levelsCritical illnessBody mass indexDistress syndromeProtein 3Acute PhysiologyMass indexFactor 1Chronic Health Evaluation III scoreInsulin-like growth factor-1 levelsChronic Health Evaluation IIISepsis/septic shockGrowth factor-1 levelsTotal insulin-like growth factor-1Insulin-like growth factorAcute critical illnessAcute hepatic dysfunctionReceipt of corticosteroidsLarge prospective studiesPersonalized Critical Care Medicine: How Far Away Are We?
Ahasic AM, Christiani DC. Personalized Critical Care Medicine: How Far Away Are We? Seminars In Respiratory And Critical Care Medicine 2015, 36: 809-822. PMID: 26595041, DOI: 10.1055/s-0035-1564852.Peer-Reviewed Original ResearchConceptsCritical illnessClinical trialsAcute respiratory distress syndromeRespiratory distress syndromeIntensive care unitCritical care arenaDirect patient careUnique risk factorsMulti-biomarker panelAccurate diagnostic classificationMajor clinical applicationsPrecise medical careDistress syndromeCare unitPoor outcomeRisk factorsTreatment decisionsIndividual patientsClinical careClinical utilitySuch biomarkersMedical carePatient careClinical useIllness
2014
Functional status after critical illness: agreement between patient and proxy assessments
Ahasic AM, Van Ness PH, Murphy TE, Araujo KL, Pisani MA. Functional status after critical illness: agreement between patient and proxy assessments. Age And Ageing 2014, 44: 506-510. PMID: 25324334, PMCID: PMC4411220, DOI: 10.1093/ageing/afu163.Peer-Reviewed Original ResearchConceptsMonths post-ICU dischargePost-ICU dischargeFunctional statusCritical illnessInter-observer agreementICU admissionOlder patientsExact testIntensive care unit admissionProxy assessmentsPremorbid functional statusCare unit admissionBaseline functional statusCurrent functional statusMcNemar's exact testUnit admissionICU dischargeMedical ICUNeuropsychological morbidityInstrumental ADLCognitive dysfunctionDaily livingPatientsCognitive impairmentParent cohort