2024
An update on the global disparities in kidney disease burden and care across world countries and regions
Bello A, Okpechi I, Levin A, Ye F, Damster S, Arruebo S, Donner J, Caskey F, Cho Y, Davids M, Davison S, Htay H, Jha V, Lalji R, Malik C, Nangaku M, See E, Sozio S, Tonelli M, Wainstein M, Yeung E, Johnson D, Group I, Abu-Alfa A, Amouzegar A, Anand S, Arogundade F, Ashuntantang G, Bavanandan S, Coppo R, Diongole H, Divyaveer S, Ekrikpo U, Ethier I, Fung W, Gaipov A, Ghimire A, Houston G, Ibrahim K, Irish G, Jindal K, Kelly D, Lightstone L, Madero M, Nalado A, Neuen B, Olanrewaju T, Osman M, Parekh R, Petrova A, Prasad N, Prikhodina L, Racki S, Riaz P, Saad S, Sakajiki A, Savaj S, Shah D, Suzuki Y, Tesar V, Tiv S, Tungsanga S, Tzanno-Martins C, Viecelli A, Wang A, Wong M, Zaidi D. An update on the global disparities in kidney disease burden and care across world countries and regions. The Lancet Global Health 2024, 12: e382-e395. PMID: 38365413, DOI: 10.1016/s2214-109x(23)00570-3.Peer-Reviewed Original ResearchConceptsConservative kidney managementLow-resource settingsCountry income levelKidney replacement therapyKidney careHealth workforce shortagesWHO building blocksLiterature review of published reportsGlobal Kidney Health AtlasWorld Bank income groupsKidney care deliveryBurden of chronic kidney diseaseBurden of kidney diseaseGlobal burden of kidney diseaseAnnual median costsChronic kidney diseaseHigh-income countriesKidney disease burdenPhases of data collectionPrevalence of chronic kidney diseaseIncome levelPoint of deliveryAffordability of medicinesCare deliveryWorkforce shortages
2023
Biospecimen Repositories in Low- and Middle-Income Countries: Insights From an American University of Beirut and Memorial Sloan Kettering Collaboration.
Faraj W, Robson M, Tawil A, Reuter V, Mahfouz R, Cambria R, Saheb N, Ferrer C, Vemuri S, Yaghi M, Kanso M, Abdullah A, El Nounou G, Jabbour M, Muenkel K, Kaufman K, Wakim J, Badson S, Wilson R, Houston C, Drobnjak M, Hoballah J, Ziyadeh F, Zaatari G, Brennan M, O'Reilly E, Abu-Alfa A, Abou-Alfa G. Biospecimen Repositories in Low- and Middle-Income Countries: Insights From an American University of Beirut and Memorial Sloan Kettering Collaboration. JCO Global Oncology 2023, 9: e2300140. PMID: 37883726, PMCID: PMC10846789, DOI: 10.1200/go.23.00140.Peer-Reviewed Original ResearchConceptsMemorial Sloan-Kettering Cancer CenterMiddle-income countriesPatients age 18 yearsBiospecimen repositoryPatient participation ratesAge 18 yearsPotential participantsDocumentation of reasonsPrimary physicianCancer CenterJoint tissuesTherapeutic interventionsBody sitesPatientsAbnormal tissueConsentFamily membersTissueResearch awarenessAUBParticipation ratesBiospecimensParticipantsCancer genomicsKidney failure in Sudan: thousands of lives at risk
Hassan H, Hafez M, Luyckx V, Tuğlular S, Abu-Alfa A. Kidney failure in Sudan: thousands of lives at risk. The Lancet 2023, 402: 607. PMID: 37572679, DOI: 10.1016/s0140-6736(23)01370-3.Peer-Reviewed Original ResearchISPD Catheter-related Infection Recommendations: 2023 Update
Chow K, Li P, Cho Y, Abu-Alfa A, Bavanandan S, Brown E, Cullis B, Edwards D, Ethier I, Hurst H, Ito Y, de Moraes T, Morelle J, Runnegar N, Saxena A, So S, Tian N, Johnson D. ISPD Catheter-related Infection Recommendations: 2023 Update. Advances In Peritoneal Dialysis 2023, 43: 201-219. PMID: 37232412, DOI: 10.1177/08968608231172740.Peer-Reviewed Original ResearchConceptsDialysis catheter-related infectionsExit-site infection rateAntibiotic treatment durationCatheter exit siteExit-site infectionDuration of therapyCatheter-related infectionsImportant risk factorExit siteCatheter lossCatheter removalTunnel infectionSite infectionCuff removalAntibiotic creamCatheter interventionRisk factorsTreatment durationClinical monitoringInfection rateInfectionNew targetsNew recommendationsDurationPeritonitis
2021
Controversies in optimal anemia management: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Conference
Babitt J, Eisenga M, Haase V, Kshirsagar A, Levin A, Locatelli F, Małyszko J, Swinkels D, Tarng D, Cheung M, Jadoul M, Winkelmayer W, Drüeke T, Participants C, Abu-Alfa A, Afsar B, Pai A, Besarab A, Moore G, Casadevall N, Cases A, de Francisco A, Eckardt K, Fishbane S, Fried L, Ganz T, Ginzburg Y, Gómez R, Goodnough L, Hamano T, Hanudel M, Hao C, Iseki K, Ix J, Johansen K, Ketteler M, Kovesdy C, Leaf D, Macdougall I, Massy Z, McMahon L, Minutolo R, Nakanishi T, Nemeth E, Obrador G, Parfrey P, Park H, Pecoits-Filho R, Robinson B, Roger S, Shah Y, Spinowitz B, Tanaka T, Tsukamoto Y, Tungsanga K, Walther C, Wang A, Wolf M. Controversies in optimal anemia management: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Conference. Kidney International 2021, 99: 1280-1295. PMID: 33839163, DOI: 10.1016/j.kint.2021.03.020.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsChronic kidney diseaseKidney diseaseAnemia guidelinesHypoxia-inducible factor prolyl hydroxylase inhibitorOptimal anemia managementErythropoiesis-stimulating agentsTreatment of anemiaIron homeostasisSignificant adverse consequencesControversies ConferenceIron therapyAnemia managementRandomized trialsDiagnostic challengePatient outcomesEpidemiological studiesHydroxylase inhibitorTreatment targetsGlobal outcomeLatest evidenceDiseaseAnemiaPrevious recommendationsAdverse consequencesOngoing controversyGroup II GBCM Can Be Used Safely for Imaging in Stage 4/5 CKD Patients: COMMENTARY.
Abu-Alfa A. Group II GBCM Can Be Used Safely for Imaging in Stage 4/5 CKD Patients: COMMENTARY. Kidney360 2021, 2: 16-19. PMID: 35378016, PMCID: PMC8785741, DOI: 10.34067/kid.0006002020.Commentaries, Editorials and Letters
2020
Collagenofibrotic glomerulopathy in a kidney transplant recipient: A first report
Jdiaa SS, Moeckel GW, Kfoury H, Medawar WA, Abu‐Alfa A. Collagenofibrotic glomerulopathy in a kidney transplant recipient: A first report. American Journal Of Transplantation 2020, 21: 1948-1952. PMID: 33206467, DOI: 10.1111/ajt.16399.Peer-Reviewed Case Reports and Technical NotesConceptsKidney transplant recipientsCollagenofibrotic glomerulopathyTransplant recipientsRenal dysfunctionType 3 fibresProgressive diseaseKidney diseaseDefinitive diagnosisUnknown causeRare diseaseDiseaseFirst caseRecipientsFirst reportHematuriaProteinuriaGlomerulopathyPatientsDysfunctionGlomeruliDiagnosisProgressionThe Case | Severe high-anion gap metabolic acidosis
Jdiaa SS, Abu-Alfa AK. The Case | Severe high-anion gap metabolic acidosis. Kidney International 2020, 98: 1625-1626. PMID: 33276873, DOI: 10.1016/j.kint.2020.06.013.Peer-Reviewed Case Reports and Technical NotesKDIGO Controversies Conference on onco-nephrology: kidney disease in hematological malignancies and the burden of cancer after kidney transplantation
Małyszko J, Bamias A, Danesh F, Dębska-Ślizień A, Gallieni M, Gertz M, Kielstein J, Tesarova P, Wong G, Cheung M, Wheeler D, Winkelmayer W, Porta C, Participants C, Abu-Alfa A, Amer H, Beutel G, Chapman J, Chen X, Chudek J, Cosmai L, Danesi R, De Stefano F, Iseki K, Jaimes E, Jhaveri K, Jurczyszyn A, Kazancioğlu R, Kitchlu A, Kollmannsberger C, Lahoti A, Li Y, Macía M, Matsubara T, Mitropoulos D, Noiri E, Perazella M, Ronco P, Rosner M, Romeo M, Sprangers B, Stadler W, Stevens P, Tesař V, da Costa e Silva V, Vesole D, Vijayan A, Viklický O, Workeneh B, Yanagita M, Zakharova E. KDIGO Controversies Conference on onco-nephrology: kidney disease in hematological malignancies and the burden of cancer after kidney transplantation. Kidney International 2020, 98: 1407-1418. PMID: 33276867, DOI: 10.1016/j.kint.2020.07.012.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsChronic kidney diseaseKidney diseaseHematological malignanciesControversies ConferenceKidney transplantationModerate stage chronic kidney diseaseKDIGO Controversies ConferenceAcute kidney injuryKidney transplant recipientsBurden of cancerKidney injuryTransplant recipientsKidney transplantRegistry analysisMultiple myelomaClinical challengeCancer riskGlobal outcomeMalignancyCancerPatientsDiseaseTransplantationBidirectional relationshipRiskStrategic plan for integrated care of patients with kidney failure
Harris DCH, Davies SJ, Finkelstein FO, Jha V, Bello AK, Brown M, Caskey FJ, Donner JA, Liew A, Muller E, Naicker S, O’Connell P, Filho RP, Vachharajani T, Groups S, Abu Alfa A, Ashuntantang G, Brown E, Cullis B, Dreyer G, Eke F, Garcia G, Goh B, Hemmelgarn B, Hou F, Iyengar A, Johnson D, Levin N, Luyckx V, Martin D, McCulloch M, Mengistu Y, Moosa M, Morton R, Niang A, Obrador G, Okpechi I, Ossareh S, Shah K, Sola L, Swanepoel C, Tchokhonelidze I, Tonelli M, Trask M, Kazancioglu R, Twahir A, Walker R, Were A, Yang C, Yeates K, Zakharova E, Zuniga C. Strategic plan for integrated care of patients with kidney failure. Kidney International 2020, 98: s117-s134. PMID: 33126957, DOI: 10.1016/j.kint.2020.07.023.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsKDIGO Controversies Conference on onco-nephrology: understanding kidney impairment and solid-organ malignancies, and managing kidney cancer
Porta C, Bamias A, Danesh F, Dębska-Ślizień A, Gallieni M, Gertz M, Kielstein J, Tesarova P, Wong G, Cheung M, Wheeler D, Winkelmayer W, Małyszko J, Participants C, Abu-Alfa A, Amer H, Beutel G, Chapman J, Chen X, Chudek J, Cosmai L, Danesi R, De Stefano F, Iseki K, Jaimes E, Jhaveri K, Jurczyszyn A, Kazancioğlu R, Kitchlu A, Kollmannsberger C, Lahoti A, Li Y, Macía M, Matsubara T, Mitropoulos D, Noiri E, Perazella M, Ronco P, Rosner M, Romeo M, Sprangers B, Stadler W, Stevens P, Tesař L, da Costa e Silva V, Vesole D, Vijayan A, Viklický O, Workeneh B, Yanagita M, Zakharova E. KDIGO Controversies Conference on onco-nephrology: understanding kidney impairment and solid-organ malignancies, and managing kidney cancer. Kidney International 2020, 98: 1108-1119. PMID: 33126977, DOI: 10.1016/j.kint.2020.06.046.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsChronic kidney diseaseSolid organ malignanciesControversies ConferenceKidney impairmentKidney diseaseKidney cancerKDIGO Controversies ConferenceSetting of malignancyIncidence of cancerAreas of controversyOrgan malignanciesTreatment landscapeKidney functionOncology patientsMedical oncologyPalliative careRenal issuesPatient outcomesNovel therapiesCritical careMalignancyAnticancer treatmentCancerPatientsCancer treatmentUse of Gadolinium-Based Contrast Agents in Kidney Disease Patients: Time for Change
Abu-Alfa AK. Use of Gadolinium-Based Contrast Agents in Kidney Disease Patients: Time for Change. American Journal Of Kidney Diseases 2020, 76: 436-439. PMID: 32283121, DOI: 10.1053/j.ajkd.2020.03.011.Commentaries, Editorials and Letters
2019
May Measurement Month 2018: a pragmatic global screening campaign to raise awareness of blood pressure by the International Society of Hypertension
Beaney T, Burrell L, Castillo R, Charchar F, Cro S, Damasceno A, Kruger R, Nilsson P, Prabhakaran D, Ramirez A, Schlaich M, Schutte A, Tomaszewski M, Touyz R, Wang J, Weber M, Poulter N, Burazeri G, Qirjako G, Roshi E, Cunashi R, Fernandes M, Pereira S, Neto M, Oliveira P, Feijão A, Cerniello Y, Marin M, Vasquez F, Espeche W, Stisman D, Fuentes I, Zilberman J, Rodriguez P, Babinyan K, Engibaryan A, Avagyan A, Minasyan A, Gevorkyan A, Carnagarin R, Carrington M, Sharman J, Lee R, Perl S, Niederl E, Malik F, Choudhury S, Al Mamun M, Ishraquzzaman M, Anthony F, Connell K, De Backer T, Krzesinski J, Houenassi M, Houehanou C, Sokolovic S, Bahtijarevic R, Tiro M, Mosepele M, Masupe T, Barroso W, Gomes M, Feitosa A, Brandão A, Miranda R, Azevedo V, Dias L, Garcia G, Martins I, Dzudie A, Kingue S, Djomou F, Njume E, Khan N, Lanas F, Garcia M, Paccot M, Torres P, Li Y, Liu M, Xu L, Li L, Chen X, Deng J, Zhao W, Fu L, Zhou Y, Lopez-Jaramillo P, Otero J, Camacho P, Accini J, Sanchez G, Arcos E, M’Buyamba-Kabangu J, Katamba F, Ngoyi G, Buila N, Bayauli P, Mbolla B, Bakekolo P, Landa C, Kaky G, Kramoh E, Ngoran Y, Olsen M, Valoy L, Santillan M, Rafael G, Peñaherrera C, Villalba J, Ramirez M, Arteaga F, Delgado P, Beistline H, Cappuccio F, Keitley J, Tay T, Goshu D, Kassie D, Gebru S, Pathak A, Denolle T, Tsinamdzgvrishvili B, Trapaidze D, Sturua L, Abesadze T, Grdzelidze N, Grabfelder M, Krämer B, Schmeider R, Twumasi-Ankrah B, Tannor E, Lincoln M, Deku E, Quintana F, Kenerson J, Baptiste E, Saintilmond W, Barrientos A, Peiger B, Lagos A, Forgas M, Lee V, Tomlinson B, Járai Z, Páll D, More A, Maheshwari A, Verma N, Sharma M, Mukherjee T, Patil M, Jose A, More A, Takalkar A, Turana Y, Widyantoro B, Danny S, Djono S, Handari S, Tambunan M, Tiksnadi B, Hermiawaty E, Tavassoli E, Zolfaghari M, Dolan E, O'Brien E, Borghi C, Ferri C, Torlasco C, Parati G, Nwokocha C, Nwokocha M, Ogola E, Gitura B, Barasa A, Barasa F, Wairagu A, Nalwa W, Najem R, Abu Alfa A, Fageh H, Msalam O, Derbi H, Bettamar K, Zakauskiene U, Vickiene A, Calmes J, Alkerwi A, Gantenbein M, Ndhlovu H, Masiye J, Chirwa M, Nyirenda N, Dhlamini T, Chia Y, Ching S, Devaraj N, Ouane N, Fane T, Kowlessur S, Ori B, Heecharan J, Alcocer L, Chavez A, Ruiz G, Espinosa C, Gomez-Alvarez E, Neupane D, Bhattarai H, Ranabhat K, Adhikari T, Koirala S, Toure I, Soumana K, Wahab K, Omotoso A, Sani M, Okubadejo N, Nadar S, Al-Riyami H, Ishaq M, Memon F, Sidique S, Choudhry H, Khan R, Ayala M, Maidana A, Bogado G, Ona D, Atilano A, Granada C, Bartolome R, Manese L, Mina A, Dumlao M, Villaruel M, Gomez L, Jóźwiak J, Małyszko J, Banach M, Mastej M, de Carvalho Rodrigues M, Martins L, Paval A, Dorobantu M, Konradi A, Chazova I, Rotar O, Spoares M, Viegas D, Almustafa B, Alshurafa S, Brady A, Bovet P, Viswanathan B, Oladapo O, Russell J, Brguljan-Hitij J, Bozic N, Knez J, Dolenc P, Hassan M, Woodiwiss A, Myburgh C, Vally M, Ruilope L, Molinero A, Rodilla E, Gijón-Conde T, Beheiry H, Ali I, Osman A, fahal N, Osman H, Altahir F, Persson M, Wuerzner G, Burkard T, Wang T, Lin H, Pan H, Chen W, Lin E, Mondo C, Ingabire P, Khomazyuk T, Krotova V, Negresku E, Evstigneeva O, Bazargani N, Agrawal A, Bin Belaila B, Suhail A, Muhammed K, Shuri H, Wainford R, Levy P, Boggia J, Garré L, Hernandez-Hernandez R, Octavio-Seijas J, Lopez-Rivera J, Morr I, Duin A, Huynh M, Cao S, Nguyen V, To M, Phan H, Cockroft J, McDonnell B, Goma F, Syatalimi C, Chifamba J, Gwini R, Tiburcio O, Xia X. May Measurement Month 2018: a pragmatic global screening campaign to raise awareness of blood pressure by the International Society of Hypertension. European Heart Journal 2019, 40: 2006-2017. PMID: 31041440, PMCID: PMC6600128, DOI: 10.1093/eurheartj/ehz300.Peer-Reviewed Original ResearchConceptsMay Measurement MonthBlood pressureAntihypertensive medicationsMeasurement MonthDiastolic blood pressureSystolic blood pressureHigh blood pressureSystematic screening programmeMore participantsMMM 2018Untreated hypertensionBP readingsFormal screeningBP measurementsDisease burdenMultiple imputationHypertensionScreening programMedicationsMmHgInternational SocietyMonthsScreening campaignParticipantsIndividualsHeart failure in chronic kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference
House A, Wanner C, Sarnak M, Piña I, McIntyre C, Komenda P, Kasiske B, Deswal A, deFilippi C, Cleland J, Anker S, Herzog C, Cheung M, Wheeler D, Winkelmayer W, McCullough P, Participants C, Abu-Alfa A, Amann K, Aonuma K, Appel L, Baigent C, Bakris G, Banerjee D, Boletis J, Bozkurt B, Butler J, Chan C, Costanzo M, Dubin R, Filippatos G, Gikonyo B, Gikonyo D, Hajjar R, Iseki K, Ishii H, Knoll G, Lenihan C, Lentine K, Lerma E, Macedo E, Mark P, Noiri E, Palazzuoli A, Pecoits-Filho R, Pitt B, Rigatto C, Rossignol P, Setoguchi S, Sood M, Störk S, Suri R, Szummer K, Tang S, Tangri N, Thompson A, Vijayaraghavan K, Walsh M, Wang A, Weir M. Heart failure in chronic kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference. Kidney International 2019, 95: 1304-1317. PMID: 31053387, DOI: 10.1016/j.kint.2019.02.022.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsChronic kidney diseaseDialysis-dependent chronic kidney diseaseNondialysis chronic kidney diseaseHeart failureKidney diseaseEjection fractionGlobal outcomeKidney transplant patientsReduced ejection fractionControversies ConferenceTransplant patientsBreakout group discussionsDiseaseOutcomesFailureHFpEFPatientsGroup discussionsPrevalenceIncidenceDiagnosisPreventionDialysis initiation, modality choice, access, and prescription: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference
Chan C, Blankestijn P, Dember L, Gallieni M, Harris D, Lok C, Mehrotra R, Stevens P, Wang A, Cheung M, Wheeler D, Winkelmayer W, Pollock C, Participants C, Abu-Alfa A, Bargman J, Bleyer A, Brown E, Davenport A, Davies S, Finkelstein F, Flythe J, Goffin E, Golper T, Gómez R, Hamano T, Hecking M, Heimbürger O, Hole B, Hothi D, Ikizler T, Isaka Y, Iseki K, Jha V, Kawanishi H, Kerr P, Komenda P, Kovesdy C, Lacson E, Laville M, Lee J, Lerma E, Levin N, Lichodziejewska-Niemierko M, Liew A, Lindley E, Lockridge R, Madero M, Massy Z, McCann L, Meyer K, Morton R, Nadeau-Fredette A, Okada H, Perez J, Perl J, Polkinghorne K, Riella M, Robinson B, Rocco M, Rosansky S, Rotmans J, Roblero M, Tangri N, Tonelli M, Tong A, Tsukamoto Y, Tungsanga K, Vachharajani T, van Loon I, Watnick S, Weiner D, Wilkie M, Zakharova E. Dialysis initiation, modality choice, access, and prescription: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference. Kidney International 2019, 96: 37-47. PMID: 30987837, DOI: 10.1016/j.kint.2019.01.017.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsEnd-stage kidney diseaseDialysis initiationKidney diseaseModality choiceGoals of careNumber of patientsPatient-centered goalsDiverse health care systemsHealth care jurisdictionsAreas of controversyHealth care systemControversies ConferenceMaintenance dialysisDialysis modalityPatient goalsPatient educationIndividualized carePatient involvementPatient experienceGlobal outcomeCare systemDialysisPatientsOutcomesDiseaseIncreasing access to integrated ESKD care as part of universal health coverage
Harris DCH, Davies SJ, Finkelstein FO, Jha V, Donner JA, Abraham G, Bello AK, Caskey FJ, Garcia GG, Harden P, Hemmelgarn B, Johnson DW, Levin NW, Luyckx VA, Martin DE, McCulloch MI, Moosa MR, O’Connell P, Okpechi IG, Filho R, Shah KD, Sola L, Swanepoel C, Tonelli M, Twahir A, van Biesen W, Varghese C, Yang CW, Zuniga C, Summit W, Abu Alfa A, Aljubori H, Alrukhaimi M, Andreoli S, Ashuntantang G, Bellorin-Font E, Bernieh B, Ibhais F, Blake P, Brown M, Brown E, Bunnag S, Chan T, Chen Y, Granado R, Claus S, Collins A, Couchoud C, Cueto-Manzano A, Cullis B, Douthat W, Dreyer G, Eiam-Ong S, Eke F, Feehally J, Ghnaimat M, Goh B, Hassan M, Hou F, Jager K, Kalantar-Zadeh K, Kazancioglu R, Levin A, Liew A, McKnight M, Mengistu Y, Morton R, Muller E, Murtagh F, Naicker S, Nangaku M, Niang A, Obrador G, Ossareh S, Perl J, Rahman M, Rashid H, Richards M, Rondeau E, Sahay M, Saleh A, Schneditz D, Tchokhonelidze I, Tesar V, Trask M, Tungsanga K, Vachharajani T, Walker R, Walker R, Were A, Yao Q, Yeates K, Yu X, Zakharova E, Zemchenkov A, Zhao M. Increasing access to integrated ESKD care as part of universal health coverage. Kidney International 2019, 95: s1-s33. PMID: 30904051, DOI: 10.1016/j.kint.2018.12.005.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2018
Improving the prognosis of patients with severely decreased glomerular filtration rate (CKD G4+): conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference
Eckardt K, Bansal N, Coresh J, Evans M, Grams M, Herzog C, James M, Heerspink H, Pollock C, Stevens P, Tamura M, Tonelli M, Wheeler D, Winkelmayer W, Cheung M, Hemmelgarn B, Participants C, Abu-Alfa A, Anand S, Arici M, Ballew S, Block G, Burgos-Calderon R, Charytan D, Das-Gupta Z, Dwyer J, Fliser D, Froissart M, Gill J, Griffith K, Harris D, Huffman K, Inker L, Jager K, Jun M, Kalantar-Zadeh K, Kasiske B, Kovesdy C, Krane V, Lamb E, Lerma E, Levey A, Levin A, Mauro J, Nash D, Navaneethan S, O’Donoghue D, Obrador G, Pecoits-Filho R, Robinson B, Schäffner E, Segev D, Stengel B, Stenvinkel P, Tangri N, Tentori F, Tsukamoto Y, Turakhia M, Vazquez M, Wang A, Williams A. Improving the prognosis of patients with severely decreased glomerular filtration rate (CKD G4+): conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference. Kidney International 2018, 93: 1281-1292. PMID: 29656903, PMCID: PMC5998808, DOI: 10.1016/j.kint.2018.02.006.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsGlomerular filtration rateKidney replacement therapyCKD G4Kidney failureFiltration rateRisk factorsGlobal outcomeTraditional CVD risk factorsCKD Prognosis ConsortiumCVD risk factorsCardiovascular disease eventsPrognosis of patientsOptimal therapeutic strategyControversies ConferenceCohort studyCVD outcomesHeart failureVariable prognosisClinical outcomesTherapeutic challengeKidney diseasePrognostic valueReplacement therapyInternational expert groupPatient preferencesKidney disease in the setting of HIV infection: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference
Swanepoel C, Atta M, D’Agati V, Estrella M, Fogo A, Naicker S, Post F, Wearne N, Winkler C, Cheung M, Wheeler D, Winkelmayer W, Wyatt C, Participants C, Abu-Alfa A, Adu D, Agodoa L, Alpers C, Arogundade F, Ashuntantang G, Bagnis C, Bhimma R, Brocheriou I, Cohen A, Cohen K, Cook H, de Seigneux S, Fabian J, Finkelstein F, Haas M, Hamzah L, Hendry B, Imonje V, Jennette J, Kimmel P, Klotman M, Klotman P, Larsen C, McCulloch M, Mosiane P, Nast C, Okpechi I, Ray P, Rosenberg A, Ross M, Ryom L, Truong L, Ulasi I, Vogt L, Zeier M. Kidney disease in the setting of HIV infection: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference. Kidney International 2018, 93: 545-559. PMID: 29398134, PMCID: PMC5983378, DOI: 10.1016/j.kint.2017.11.007.Peer-Reviewed Original ResearchConceptsHIV-positive individualsKidney diseaseAntiretroviral therapyHIV infectionImmune complex kidney diseaseKidney disease preventionHIV-associated nephropathyFocal segmental glomerulosclerosisUnique HIVKidney injuryOpportunistic infectionsHIV treatmentClinical guidelinesRenal pathologySegmental glomerulosclerosisGeneral populationRole of geneticsGlobal outcomeDisease preventionNatural historyInfectious diseasesDiseaseInfectionGenetic factorsPrevention
2015
Hypertensive Encephalopathy and Renal Failure in a Young Man
Hunter RW, Dominiczak AF, Alwakeel J, Staessen JA, Jennings GL, Abu-Alfa AK, Webb DJ, Dhaun N. Hypertensive Encephalopathy and Renal Failure in a Young Man. Hypertension 2015, 67: 6-13. PMID: 26597825, DOI: 10.1161/hypertensionaha.115.06651.Peer-Reviewed Case Reports and Technical Notes
2014
Advancing pharmacovigilance through academic–legal collaboration: the case of gadolinium-based contrast agents and nephrogenic systemic fibrosis—a research on adverse drug events and reports (RADAR) report
Edwards BJ, Laumann AE, Nardone B, Miller FH, Restaino J, Raisch DW, McKoy JM, Hammel JA, Bhatt K, Bauer K, Samaras AT, Fisher MJ, Bull C, Saddleton E, Belknap SM, Thomsen HS, Kanal E, Cowper SE, Abu Alfa AK, West DP. Advancing pharmacovigilance through academic–legal collaboration: the case of gadolinium-based contrast agents and nephrogenic systemic fibrosis—a research on adverse drug events and reports (RADAR) report. British Journal Of Radiology 2014, 87: 20140307. PMID: 25230161, PMCID: PMC4170864, DOI: 10.1259/bjr.20140307.Peer-Reviewed Original ResearchConceptsGadolinium-based contrast agentsAdverse drug eventsDrug eventsMedicines AgencyGadopentetate dimeglumineDrug Administration Adverse Event Reporting SystemAdverse Event Reporting SystemDanish Medicines AgencyNephrogenic systemic fibrosisEvent Reporting SystemEuropean Medicines AgencyNSF casesHistopathological dataContrast agentsSystemic fibrosisDrug AdministrationLegal data setsUnconfounded casesGadobenate dimeglumineMean numberDimeglumineReporting systemPharmacovigilance researchSafety informationPharmacovigilance