2024
Deep learning for prediction of post-thrombectomy outcomes based on admission CT angiography in large vessel occlusion stroke
Sommer J, Dierksen F, Zeevi T, Tran A, Avery E, Mak A, Malhotra A, Matouk C, Falcone G, Torres-Lopez V, Aneja S, Duncan J, Sansing L, Sheth K, Payabvash S. Deep learning for prediction of post-thrombectomy outcomes based on admission CT angiography in large vessel occlusion stroke. Frontiers In Artificial Intelligence 2024, 7: 1369702. PMID: 39149161, PMCID: PMC11324606, DOI: 10.3389/frai.2024.1369702.Peer-Reviewed Original ResearchEnd-to-endComputed tomography angiographyLarge vessel occlusionConvolutional neural networkDeep learning pipelineTrain separate modelsLogistic regression modelsResNet-50Deep learningAdmission computed tomography angiographyNeural networkLearning pipelineAdmission CT angiographyPreprocessing stepDiagnosis of large vessel occlusionsLarge vessel occlusion strokeReceiver operating characteristic areaEnsemble modelAutomated modelPre-existing morbidityCT angiographyReperfusion successNeurological examCross-validationOcclusion stroke
2020
Effects of Collateral Status on Infarct Distribution Following Endovascular Therapy in Large Vessel Occlusion Stroke
Al-Dasuqi K, Payabvash S, Torres-Flores GA, Strander SM, Nguyen CK, Peshwe KU, Kodali S, Silverman A, Malhotra A, Johnson MH, Matouk CC, Schindler JL, Sansing LH, Falcone GJ, Sheth KN, Petersen NH. Effects of Collateral Status on Infarct Distribution Following Endovascular Therapy in Large Vessel Occlusion Stroke. Stroke 2020, 51: e193-e202. PMID: 32781941, PMCID: PMC7484023, DOI: 10.1161/strokeaha.120.029892.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overArterial Occlusive DiseasesCerebral InfarctionCohort StudiesCollateral CirculationComputed Tomography AngiographyEndovascular ProceduresFemaleHumansInfarction, Middle Cerebral ArteryLinear ModelsMagnetic Resonance AngiographyMaleMiddle AgedReperfusionRetrospective StudiesStrokeThrombectomyTreatment OutcomeWhite MatterConceptsLarge vessel occlusion strokeFinal infarct volumeCollateral statusPoor collateral statusFavorable outcomeInfarct distributionInfarct volumeReperfusion successIndependent predictorsOcclusion strokeInternal capsuleAnterior circulation large vessel occlusion ischemic strokeLarge vessel occlusion ischemic strokeDeep white matter tractsBaseline collateral statusBorder-zone infarctionEarly favorable outcomeEarly functional outcomesRankin Scale scoreCohort of patientsDegree of reperfusionLarge vessel occlusionComputed tomography angiographyDeep white matterMagnetic resonance imaging
2019
Cost-Effectiveness of Computed Tomography Angiography in Management of Tiny Unruptured Intracranial Aneurysms in the United States
Wu X, Matouk CC, Mangla R, Forman HP, Gandhi D, Sanelli P, Malhotra A. Cost-Effectiveness of Computed Tomography Angiography in Management of Tiny Unruptured Intracranial Aneurysms in the United States. Stroke 2019, 50: 2396-2403. PMID: 31340732, DOI: 10.1161/strokeaha.119.025600.Peer-Reviewed Original ResearchConceptsComputed tomography angiographyUnruptured intracranial aneurysmsIntracranial aneurysmsTomography angiographyCancer riskCTA surveillanceCost-effective strategyRadiation-induced brain tumorsRadiation-induced cancer riskSubsequent magnetic resonanceBrain cancer riskBetter health outcomesAnnual rupture riskProbabilistic sensitivity analysesRupture riskLower healthcare spendingAggressive managementPatients 30Subarachnoid hemorrhageIncidental detectionPrior historyHigh riskBrain tumorsAneurysmsHealth outcomes
2018
Letter to the Editor. Computed tomography angiography for the diagnosis of blunt cerebrovascular injury.
Malhotra A, Wu X, Tu L, Seifert K. Letter to the Editor. Computed tomography angiography for the diagnosis of blunt cerebrovascular injury. Journal Of Neurosurgery 2018, 129: 265-267. PMID: 29749913, DOI: 10.3171/2017.11.jns172884.Peer-Reviewed Original ResearchLetter to the Editor Regarding “Yield of Computed Tomography (CT) Angiography in Patients with Acute Headache, Normal Neurological Examination, and Normal Non Contrast CT: A Meta-Analysis”
Malhotra A, Wu X, Seifert K, Tu L. Letter to the Editor Regarding “Yield of Computed Tomography (CT) Angiography in Patients with Acute Headache, Normal Neurological Examination, and Normal Non Contrast CT: A Meta-Analysis”. Journal Of Stroke And Cerebrovascular Diseases 2018, 27: 2043. PMID: 29571755, DOI: 10.1016/j.jstrokecerebrovasdis.2018.02.049.Peer-Reviewed Original Research
2016
Should Patients Be Counseled About Possible Recurrence of Perimesencephalic Subarachnoid Hemorrhage?
Malhotra A, Wu X, Borse R, Matouk CC, Bulsara K. Should Patients Be Counseled About Possible Recurrence of Perimesencephalic Subarachnoid Hemorrhage? World Neurosurgery 2016, 94: 580.e17-580.e22. PMID: 27521726, DOI: 10.1016/j.wneu.2016.07.112.Peer-Reviewed Original ResearchConceptsPerimesencephalic subarachnoid hemorrhageAneurysmal subarachnoid hemorrhageSubarachnoid hemorrhageTomography angiographyBetter outcomesBenign natural courseNew neurologic signsComputed tomography angiographyHistory of traumaPossibility of recurrenceDigital subtraction angiographyRecurrent hemorrhageSevere headacheVascular anomaliesNeurologic signsCase reportNatural courseInitial episodeSixth decadeSubarachnoid bleedSudden onsetPossible recurrenceLower riskPatientsPrevious episodes
2015
Predictors of Vertebral Artery Injury in Isolated C2 Fractures Based on Fracture Morphology Using CT Angiography
Durand D, Wu X, Kalra VB, Abbed KM, Malhotra A. Predictors of Vertebral Artery Injury in Isolated C2 Fractures Based on Fracture Morphology Using CT Angiography. Spine 2015, 40: e713-e718. PMID: 25803220, DOI: 10.1097/brs.0000000000000893.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overCervical VertebraeDatabases, FactualFemaleHumansMaleMiddle AgedPredictive Value of TestsPrognosisRetrospective StudiesRisk AssessmentRisk FactorsSpinal FracturesTomography, X-Ray ComputedTrauma CentersVascular System InjuriesVertebral ArteryYoung AdultConceptsVertebral artery injuryC2 fracturesComputed tomography angiographyTransverse foramenTomography angiographyArtery injuryLevel I trauma centerInstitutional board review approvalTransverse foramen fracturesType III densI trauma centerVertebral body fracturesRetrospective database analysisC2 transverse foramenFracture patternsFisher's exact testMultiplanar CT scansFracture classification schemeStudent's t-testAntithrombotic treatmentNeurological sequelaeFracture hospitalizationsOccipital fractureDens fracturesTrauma centerScreening for Pediatric Blunt Cerebrovascular Injury: Review of Literature and a Cost-Effectiveness Analysis
Malhotra A, Wu X, Kalra VB, Goodman TR, Schindler J, Forman HP. Screening for Pediatric Blunt Cerebrovascular Injury: Review of Literature and a Cost-Effectiveness Analysis. Journal Of Pediatric Surgery 2015, 50: 1751-1757. PMID: 26546389, DOI: 10.1016/j.jpedsurg.2015.05.005.Peer-Reviewed Original ResearchConceptsBlunt cerebrovascular injuryPediatric blunt cerebrovascular injurySelective computed tomography angiographyComputed tomography angiographyOptimal imaging strategyCost-effectiveness analysisAnticoagulation therapyCerebrovascular injuryManagement of BCVIAppropriate anticoagulation therapyHigh-risk patientsHigh-risk factorsImaging strategiesPossible screening strategiesReview of literatureSelective anticoagulationPediatric patientsAnticoagulation complicationsTomography angiographySystematic reviewPatientsSocietal perspectiveCost-effective strategyData extractionScreening strategy