Risk factors for MACE and bleeding in atrial fibrillation patients undergoing surgery: Insights from the bridge trial
Shu L, Jack N, de Havenon A, Goldstein E, Khan F, Nguyen T, Henninger N, Siegler J, Stretz C, Perelstein E, Kala N, Rana M, Furie K, Douketis J, Yaghi S. Risk factors for MACE and bleeding in atrial fibrillation patients undergoing surgery: Insights from the bridge trial. Journal Of Stroke And Cerebrovascular Diseases 2024, 33: 107839. PMID: 38944363, DOI: 10.1016/j.jstrokecerebrovasdis.2024.107839.Peer-Reviewed Original ResearchMajor adverse cardiovascular eventsSymptomatic bleedingBridging therapyRisk factorsAtrial fibrillationLow-molecular-weight heparin bridging therapyTemporary interruption of warfarin therapyInterruption of warfarin therapyNonsteroidal anti-inflammatory drug useElective proceduresAnti-inflammatory drug useElective invasive proceduresHeparin bridging therapyRisk of adverse outcomesAdverse cardiovascular eventsPerioperative risk stratificationCox regression modelsIdentified risk factorsPost hoc analysisPatient undergoes surgeryLogistic stepwise regressionWarfarin therapyBridging anticoagulationAF patientsBleeding outcomes