2024
Multilevel determinants of antiretroviral therapy initiation and retention in the test-and-treat era of Nepal: a qualitative study
Shrestha A, Poudel L, Shrestha S, Jha N, Kuikel B, Shakya P, Kunwar R, Pandey L, KC M, Wilson E, Deuba K. Multilevel determinants of antiretroviral therapy initiation and retention in the test-and-treat era of Nepal: a qualitative study. BMC Health Services Research 2024, 24: 927. PMID: 39138448, PMCID: PMC11323673, DOI: 10.1186/s12913-024-11311-6.Peer-Reviewed Original ResearchConceptsAntiretroviral therapy initiationHealthcare providersDenial of HIV statusPerspectives of healthcare providersAntiretroviral therapyCommunity health workersStrengthening healthcare systemsART initiationHealth system levelLong-term health outcomesHealthcare system levelAntiretroviral therapy clientsChanging public health policyFear of disclosureIndividual-level facilitatorsSocio-ecological modelImplementing antiretroviral therapyAvailability of medicationsPublic health policiesAntiretroviral therapy adherencePerceived health benefitsFear of deathClient tracking systemProvision of free treatmentHealth workers
2021
Knowledge, attitude, preventive practices and utilization of cervical cancer screening among women in Nepal: a community-based cross-sectional study
Shrestha AD, Gyawali B, Shrestha A, Shrestha S, Neupane D, Ghimire S, Campbell C, Kallestrup P. Knowledge, attitude, preventive practices and utilization of cervical cancer screening among women in Nepal: a community-based cross-sectional study. European Journal Of Cancer Prevention 2021, 31: 73-81. PMID: 34871200, DOI: 10.1097/cej.0000000000000670.Peer-Reviewed Original ResearchMeSH KeywordsCross-Sectional StudiesEarly Detection of CancerFemaleHealth Knowledge, Attitudes, PracticeHumansMaleMiddle AgedNepalSurveys and QuestionnairesUterine Cervical NeoplasmsConceptsCervical cancer screeningCervical cancerPreventive practicesCancer screeningCommunity-based cross-sectional studyCommunity-based cross-sectional surveyCommunity-based educational interventionGlobal public health concernAvailability of screeningUtilization of screeningCross-sectional studyMedian knowledge scoreYears of agePublic health concernCross-sectional surveySystematic random samplingMean ageCancer deathMedian attitude scoreWomen 30Home visitsPractice scoresTreatment servicesKnowledge scoreCancer
2020
Worksite intervention study to prevent diabetes in Nepal: a randomised trial protocol
Pyakurel P, Shrestha A, Karmacharya BM, Budhathoki SS, Chaudhari RK, Tamrakar D, Shrestha A, Karmacharya RM, Shrestha A, Sharma S, Sharma SK, Spiegelman D. Worksite intervention study to prevent diabetes in Nepal: a randomised trial protocol. Open Heart 2020, 7: e001236. PMID: 32847993, PMCID: PMC7451278, DOI: 10.1136/openhrt-2019-001236.Peer-Reviewed Original ResearchMeSH KeywordsAdultBiomarkersBlood GlucoseDiabetes MellitusGlycated HemoglobinHealth BehaviorHealth Knowledge, Attitudes, PracticeHealthy LifestyleHumansMaleMiddle AgedMulticenter Studies as TopicNepalOccupational Health ServicesPatient Education as TopicPrediabetic StatePrimary PreventionRandomized Controlled Trials as TopicRisk Reduction BehaviorTime FactorsTreatment OutcomeConceptsBehavioral interventionsControl periodDiabetes risk reductionMonth control periodNepal Health Research CouncilBehavioral intervention groupWorksite intervention studiesT-testHealth Research CouncilInstitutional review boardTwo-sample t-testBlood sugarTrial protocolIntervention groupEthical approvalControl groupIntervention studiesType 2More monthsReview boardInterventionDiabetesParticipant changesPublic healthRisk reduction
2019
Nepal Pioneer Worksite Intervention Study to lower cardio-metabolic risk factors: design and protocol
Shrestha A, Tamrakar D, Karmacharya BM, Shrestha A, Shrestha R, Bhatta RD, Pyakurel P, Khudyakov P, Malik V, Mattei J, Spiegelman D. Nepal Pioneer Worksite Intervention Study to lower cardio-metabolic risk factors: design and protocol. BMC Cardiovascular Disorders 2019, 19: 48. PMID: 30819098, PMCID: PMC6393979, DOI: 10.1186/s12872-019-1025-3.Peer-Reviewed Original ResearchMeSH KeywordsCardiovascular DiseasesDiet, HealthyExerciseFemaleFood ServicesHealth Knowledge, Attitudes, PracticeHumansMaleMetabolic SyndromeNepalOccupational Health ServicesPatient Education as TopicProtective FactorsRandomized Controlled Trials as TopicRisk FactorsRisk Reduction BehaviorTime FactorsTreatment OutcomeConceptsCardio-metabolic riskWorksite intervention studiesIntervention studiesBlood sugarCardiovascular disease prevention effortsPrevention programsCardio-metabolic risk factorsBehavioral interventionsCardio-metabolic outcomesTrial registrationThe trialElevated blood pressureDiabetes Prevention ProgramCardiovascular disease burdenProportion of participantsDisease prevention effortsHealthy food choicesChi-square testEnvironmental-level changesIndividual behavioral interventionsDhulikhel HospitalBlood pressureDietary interventionPre-post designLifestyle factorsDisease burdenSocio-economic inequalities in hypertension burden and cascade of services: nationwide cross-sectional study in Nepal
Mishra SR, Ghimire S, Shrestha N, Shrestha A, Virani SS. Socio-economic inequalities in hypertension burden and cascade of services: nationwide cross-sectional study in Nepal. Journal Of Human Hypertension 2019, 33: 613-625. PMID: 30659279, DOI: 10.1038/s41371-019-0165-3.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedBlood PressureCross-Sectional StudiesEducational StatusFemaleHealth Knowledge, Attitudes, PracticeHealth Services AccessibilityHealth Status DisparitiesHealthcare DisparitiesHumansHypertensionIncomeMaleMiddle AgedNepalPrevalenceResidence CharacteristicsRisk AssessmentRisk FactorsSocial Determinants of HealthYoung AdultConceptsCascade of servicesNationwide cross-sectional studyPrevalence of hypertensionControl of hypertensionBody mass indexMulti-variable logistic regressionTreatment of hypertensionCross-sectional studyNepal Demographic Health SurveyLowest wealth quintileSocio-economic inequalitiesDemographic Health SurveyHousehold wealth statusHypertension burdenTotal hypertensivesHypertensive femalesHypertension awarenessHypertension prevalenceBlood pressureMass indexHypertension statusDisease burdenHealth SurveyHypertensionCoverage of services
2017
Awareness, Prevalence, Treatment, and Control of Hypertension in Western Nepal
Neupane D, Shrestha A, Mishra SR, Bloch J, Christensen B, McLachlan CS, Karki A, Kallestrup P. Awareness, Prevalence, Treatment, and Control of Hypertension in Western Nepal. American Journal Of Hypertension 2017, 30: 907-913. PMID: 28531244, DOI: 10.1093/ajh/hpx074.Peer-Reviewed Original ResearchMeSH KeywordsAdultAntihypertensive AgentsAwarenessBlood PressureChi-Square DistributionCross-Sectional StudiesFemaleHealth Care SurveysHealth Knowledge, Attitudes, PracticeHumansHypertensionLife StyleLogistic ModelsMaleMiddle AgedMultivariate AnalysisNepalOdds RatioPrevalenceRisk FactorsRisk Reduction BehaviorSuburban HealthTreatment OutcomeConceptsControl of hypertensionBlood pressureRisk factorsHigher body mass indexBP control targetsPrevalence of hypertensionModifiable risk factorsSex-adjusted prevalenceDiastolic blood pressureLow physical activitySystolic blood pressureBody mass indexHarmful alcohol intakeHarmful alcohol drinkersCross-sectional surveyLow-income settingsSemi-urban settingHypertension burdenHypertensive medicationsPreexisting hypertensionHypertensive participantsAntihypertensive medicinesRenal diseaseMass indexAlcohol drinkers