2015
Changes in melatonin synthesis parameters after carbon monoxide concentration increase in the cavernous sinus.
Romerowicz-Misielak M, Oren D, Sowa-Kucma M, Tabecka-Lonczynska A, Gilun P, Stefanczyk-Krzymowska S, Koziorowski M. Changes in melatonin synthesis parameters after carbon monoxide concentration increase in the cavernous sinus. Journal Of Physiology And Pharmacology 2015, 66: 505-14. PMID: 26348075.Peer-Reviewed Original ResearchConceptsOphthalmic venous bloodVenous bloodNocturnal melatonin riseMelatonin levelsMelatonin riseWinter seasonal affective disorderNocturnal melatonin peakSeasonal affective disorderHour infusionCavernous sinusVenous sinusesNon-physiological changesAutologous blood plasmaAffective disordersSynthesis of melatoninBright light effectsBloodAANAT protein levelsMelatonin peakProtein levelsAcute impactSinusTreatmentBlood plasmaParallel changes
2013
SAD and the Not-So-Single Photoreceptors
Oren DA, Koziorowski M, Desan PH. SAD and the Not-So-Single Photoreceptors. American Journal Of Psychiatry 2013, 170: 1403-1412. PMID: 23929223, DOI: 10.1176/appi.ajp.2013.13010111.Peer-Reviewed Original ResearchConceptsMolecular mechanismsSeasonal affective disorderCircannual regulationCritical regulatorTetrapyrrole pigmentsDevelopment of therapiesRole of rodsInfluence of lightPhotoreceptorsCone photoreceptorsLight treatmentAntidepressant effectsPhysiologyAnimal modelsAffective disordersRecent studiesSingle photoreceptorsPhototransductionRegulatorDisordersRegulationMechanismGasotransmitterRolePigments
1998
Heisenberg meets photobiology?
Oren D. Heisenberg meets photobiology? Science 1998, 279: 969. PMID: 9490481, DOI: 10.1126/science.279.5353.963h.Peer-Reviewed Original Research
1997
Bilirubin, Rem Sleep, and Phototransduction of Environmental Time Cues. A Hypothesis
Oren D. Bilirubin, Rem Sleep, and Phototransduction of Environmental Time Cues. A Hypothesis. Chronobiology International 1997, 14: 319-329. PMID: 9167892, DOI: 10.3109/07420529709001423.Peer-Reviewed Original ResearchConceptsBiological clockEndogenous biological clockPlant phytochromesEvolutionary roleBiological clock systemEnvironmental time cuesDifferent speciesZeitgeber signalsClock systemVisual pigmentsHeme moietyCommon molecular structurePrimary effectPhototransductionBiological rhythmsPlantsPrevailing hypothesisPigmentsSimilar chromophoresTime cuesClockAnimalsPhytochromeSpeciesBile pigments
1996
Dr. Teicher and Colleagues Reply
TEICHER M, GLOD C, OREN D, SCHWARTZ P, BROWN C, ROSENTHAL N. Dr. Teicher and Colleagues Reply. American Journal Of Psychiatry 1996, 153: 1111-1111. PMID: 8678189, DOI: 10.1176/ajp.153.8.1111.Peer-Reviewed Original Research
1991
Retinal melatonin and dopamine in seasonal affective disorder
Oren D. Retinal melatonin and dopamine in seasonal affective disorder. Journal Of Neural Transmission 1991, 83: 85-95. PMID: 2018631, DOI: 10.1007/bf01244455.Peer-Reviewed Original Research