2004
Preferential 5-HT1A Autoreceptor Occupancy by Pindolol is Attenuated in Depressed Patients: Effect of Treatment or an Endophenotype of Depression?
Rabiner E, Bhagwagar Z, Gunn R, Cowen P, Grasby P. Preferential 5-HT1A Autoreceptor Occupancy by Pindolol is Attenuated in Depressed Patients: Effect of Treatment or an Endophenotype of Depression? Neuropsychopharmacology 2004, 29: 1688-1698. PMID: 15127080, DOI: 10.1038/sj.npp.1300472.Peer-Reviewed Original ResearchMeSH KeywordsAdrenergic beta-AntagonistsAdultAutoreceptorsDepressive DisorderDose-Response Relationship, DrugFemaleHumansMaleMiddle AgedPhenotypePindololPiperazinesPsychiatric Status Rating ScalesPyridinesRadiopharmaceuticalsReceptor, Serotonin, 5-HT1ASerotonin AntagonistsTomography, Emission-Computed
2002
Acute citalopram administration produces correlated increases in plasma and salivary cortisol
Bhagwagar Z, Hafizi S, Cowen P. Acute citalopram administration produces correlated increases in plasma and salivary cortisol. Psychopharmacology 2002, 163: 118-120. PMID: 12185409, DOI: 10.1007/s00213-002-1149-4.Peer-Reviewed Original ResearchConceptsSalivary cortisol levelsCortisol levelsSelective serotonin re-uptake inhibitorsSalivary cortisolSerotonin re-uptake inhibitorsAcute citalopram administrationRe-uptake inhibitorsCross-over designSalivary cortisol concentrationsCitalopram administrationIntravenous administrationCortisol releaseHealthy volunteersCortisol concentrationsSaliva cortisolCitalopramCortisolParallel increaseAdministrationCorrelated increaseAcceptable means