Annexin-A5 monomer as a membrane repair agent for the treatment of renal ischemia-reperfusion injury
Dong Y, Jia Z, Kang B, Zhang W. Annexin-A5 monomer as a membrane repair agent for the treatment of renal ischemia-reperfusion injury. Molecular Biology Reports 2024, 51: 679. PMID: 38796668, DOI: 10.1007/s11033-024-09606-2.Peer-Reviewed Original ResearchConceptsRenal ischemia-reperfusion injuryIschemia-reperfusion injuryEffect of anxA5Bilateral renal IRIBackgroundRenal ischemia-reperfusion injuryProtective effectTreatment of renal ischemia-reperfusion injuryAcute kidney injurySimulated ischemia-reperfusion injuryEpithelial cell membranesHK-2 cellsMechanism of actionKidney injurySD ratsIn vitro experimentsTherapeutic effectPrevent cell deathMeasure cellular activityKidney structureAnnexin A5HK-2AnxA5In vitroCell deathCell membrane integrityPro-vasculogenic Fibers by PDA-Mediated Surface Functionalization Using Cell-Free Fat Extract (CEFFE)
Li D, Li Q, Xu T, Guo X, Tang H, Wang W, Zhang W, Zhang Y. Pro-vasculogenic Fibers by PDA-Mediated Surface Functionalization Using Cell-Free Fat Extract (CEFFE). Biomacromolecules 2024, 25: 1550-1562. PMID: 38411008, DOI: 10.1021/acs.biomac.3c01124.Peer-Reviewed Original ResearchConceptsFunctional biomaterial scaffoldsFunctional electrospun fibersFunctional tissue regenerationEngineered three-dimensionalTissue regenerationFibrous scaffoldsElectrospun fibersBiomaterial scaffoldsFiber surfaceBiomaterial constructsSurface functionalizationPCL/GTThree-dimensionalAdequate vascular networkPolydopamineFibersScaffoldsSustained mannerBioactive agentsCytocompatibilityVascular networkCell-free fat extract