Effectiveness and Safety of Ketamine for Unipolar Depression: a Systematic Review
Memon R, Naveed S, Faquih A, Fida A, Abbas N, Chaudhary A, Qayyum Z. Effectiveness and Safety of Ketamine for Unipolar Depression: a Systematic Review. Psychiatric Quarterly 2020, 91: 1147-1192. PMID: 32852658, DOI: 10.1007/s11126-020-09830-6.Peer-Reviewed Original ResearchMeSH KeywordsAntidepressive AgentsDepressive Disorder, MajorElectroconvulsive TherapyHumansKetamineTreatment OutcomeConceptsMajor depressive disorderElectroconvulsive therapySystematic reviewTreatment optionsMajority of studiesSafety of ketamineTolerability of ketamineTreatment-resistant depressionEffective treatment optionPossible treatment optionsCommon psychiatric disordersPredetermined eligibility criteriaPreferred Reporting ItemsMeta-Analyses (PRISMA) checklistAntidepressant effectsCochrane riskIntranasal ketamineIntravenous ketamineAcute treatmentBias toolIN routeSocioeconomic burdenDepressive disorderMultiple infusionsAdequate sample size