2021
Pathogenic BRCA2 germline variants in combined hepatocellular‐cholangiocarcinoma
Li H, Zhang X, Finberg KE, Walther Z, Jain D, Gibson J. Pathogenic BRCA2 germline variants in combined hepatocellular‐cholangiocarcinoma. Pathology International 2021, 72: 138-140. PMID: 34808016, DOI: 10.1111/pin.13188.Peer-Reviewed Original Research
2009
CASK Deletion in Intestinal Epithelia Causes Mislocalization of LIN7C and the DLG1/Scrib Polarity Complex without Affecting Cell Polarity
Lozovatsky L, Abayasekara N, Piawah S, Walther Z. CASK Deletion in Intestinal Epithelia Causes Mislocalization of LIN7C and the DLG1/Scrib Polarity Complex without Affecting Cell Polarity. Molecular Biology Of The Cell 2009, 20: 4489-4499. PMID: 19726564, PMCID: PMC2770937, DOI: 10.1091/mbc.e09-04-0280.Peer-Reviewed Original ResearchConceptsEpidermal growth factor receptorEpithelial polarityNormal localizationBasolateral membranePolarity complexMammalian orthologsCell polarityCaenorhabditis elegansMAGUK familyProtein complexesIntestinal epitheliumGrowth factor receptorLIN7CBasolateral localizationComplete knockoutCASK expressionTumor suppressorSubcellular distributionDlg1CASK deletionFactor receptorImmunofluorescence analysisErbB-2Intestinal homeostasisAppropriate localization
2005
Ileostomy Adenocarcinomas in the Setting of Ulcerative Colitis
Achneck HE, Wong IY, Kim PJ, Fernandes MA, Walther Z, Seymour NE, Jain D. Ileostomy Adenocarcinomas in the Setting of Ulcerative Colitis. Journal Of Clinical Gastroenterology 2005, 39: 396-400. PMID: 15815208, DOI: 10.1097/01.mcg.0000159216.39795.4a.Peer-Reviewed Case Reports and Technical NotesConceptsUlcerative colitisIleostomy siteLongstanding ulcerative colitisCases of adenocarcinomaSignet ring cellsAbundant extracellular mucinFamilial adenomatous polyposis coliIleostomy adenocarcinomaKock ileostomyMarked inflammationTotal proctocolectomyInitial biopsySubsequent biopsyCrohn's diseaseColon resectionNew ileostomyCytologic atypiaPrior historyExtracellular mucinAdenocarcinomaColitisIleostomyRare occurrenceDiseaseAdenomatous polyposis coli