2023
Response to: Does Liposomal Bupivacaine Injectable Suspension Peripheral Nerve Block Further Aid in Decreasing At-home Narcotic Utilization in Children and Adolescents After Anterior Cruciate Ligament Reconstruction
Walls H, Thomas E, Kain Z, Schlechter J. Response to: Does Liposomal Bupivacaine Injectable Suspension Peripheral Nerve Block Further Aid in Decreasing At-home Narcotic Utilization in Children and Adolescents After Anterior Cruciate Ligament Reconstruction. Journal Of Pediatric Orthopaedics 2023, 44: e209-e210. PMID: 37796190, DOI: 10.1097/bpo.0000000000002538.Peer-Reviewed Original ResearchDoes Liposomal Bupivacaine Injectable Suspension Peripheral Nerve Block Further Aid in Decreasing At-home Narcotic Utilization in Children and Adolescents After Anterior Cruciate Ligament Reconstruction
Walls H, Thomas E, Kain Z, Schlechter J. Does Liposomal Bupivacaine Injectable Suspension Peripheral Nerve Block Further Aid in Decreasing At-home Narcotic Utilization in Children and Adolescents After Anterior Cruciate Ligament Reconstruction. Journal Of Pediatric Orthopaedics 2023, 43: 511-515. PMID: 37400092, DOI: 10.1097/bpo.0000000000002466.Peer-Reviewed Original ResearchConceptsAnterior cruciate ligament reconstructionPeripheral nerve blocksCruciate ligament reconstructionVisual analog scaleNerve blockOpioid useLigament reconstructionAnalog scaleSingle-shot peripheral nerve blockAdductor canal nerve blockAverage opioid useHome opioid useHydrocodone/acetaminophenPain treatment satisfactionTreatment satisfaction scoresPostoperative pain managementACLR patientsOral acetaminophenOpioid usageUncontrolled painControl patientsNarcotic utilizationPostoperative dayOpioid analgesicsPain management
2001
Preoperative Anxiolysis and Postoperative Recovery in Women Undergoing Abdominal Hysterectomy
Kain Z, Sevarino F, Rinder C, Pincus S, Alexander G, Ivy M, Heninger G. Preoperative Anxiolysis and Postoperative Recovery in Women Undergoing Abdominal Hysterectomy. Anesthesiology 2001, 94: 415-422. PMID: 11374599, DOI: 10.1097/00000542-200103000-00009.Peer-Reviewed Original ResearchConceptsMorning of surgeryAbdominal hysterectomyPostoperative painAnalgesia useTreatment groupsGroup differencesLate postoperative time pointsPatient-controlled analgesia consumptionSelf-reported postoperative painPatient-controlled analgesia usePostoperative clinical courseTime pointsPostoperative time pointsMillions of patientsMinimal beneficial effectsLittle objective dataAnalgesic consumptionRecovery parametersAnalgesia consumptionIntramuscular midazolamPostoperative outcomesPostoperative periodPostoperative recoveryAbdominal surgeryClinical course
2000
Preoperative anxiety and postoperative pain in women undergoing hysterectomy A repeated-measures design
Kain Z, Sevarino F, Alexander G, Pincus S, Mayes L. Preoperative anxiety and postoperative pain in women undergoing hysterectomy A repeated-measures design. Journal Of Psychosomatic Research 2000, 49: 417-422. PMID: 11182434, DOI: 10.1016/s0022-3999(00)00189-6.Peer-Reviewed Original ResearchConceptsPostoperative pain responsePreoperative state anxietyPostoperative painPreoperative anxietyPain responseElective abdominal hysterectomyImmediate postoperative painPostoperative pain managementState anxietyAnalgesic consumptionAbdominal hysterectomyPositive predictorPerioperative periodPain managementSurgical managementMultiple time pointsPainRepeated-measures designTime pointsStudy sampleHysterectomySignificant positive predictorPerceived stressWardsAnxietyAttenuation of the Preoperative Stress Response with Midazolam
Kain Z, Sevarino F, Pincus S, Alexander G, Wang S, Ayoub C, Kosarussavadi B. Attenuation of the Preoperative Stress Response with Midazolam. Anesthesiology 2000, 93: 141-147. PMID: 10861157, DOI: 10.1097/00000542-200007000-00024.Peer-Reviewed Original ResearchConceptsPlacebo groupTreatment groupsPostoperative anxietyPreoperative sedativesPreoperative stress responsePlacebo-controlled trialFirst postoperative weekGreater reductionGlobal health indexAnalgesic consumptionIbuprofen usePlacebo injectionsPostoperative painClinical recoveryIntramuscular midazolamSurgery lengthPain recoveryPostoperative weekAnesthetic techniqueGeneral anesthesiaOutpatient surgeryPreoperative outcomesClinical significanceMidazolamSurgery
1998
The Sedative and Analgesic Sparing Effect of Music
Koch M, Kain Z, Ayoub C, Rosenbaum S. The Sedative and Analgesic Sparing Effect of Music. Anesthesiology 1998, 89: 300-306. PMID: 9710387, DOI: 10.1097/00000542-199808000-00005.Peer-Reviewed Original ResearchConceptsDuration of surgeryAnalgesic requirementsIntraoperative musicPatient-controlled intravenous opioid analgesiaAnalgesic sparing effectIntravenous opioid analgesiaIntravenous propofol sedationPostanesthesia care unitEffects of musicMusic groupDuration of stayPhase 2Phase 1Operating room noiseAlfentanil requirementsOpioid analgesiaAdverse eventsLess propofolSpinal anesthesiaAwake patientsCare unitAdverse outcomesPropofol sedationSparing effectUreteral calculi