2022
Perfectionism as a predictor of physician burnout
Martin S, Fortier M, Heyming T, Ahn K, Nichols W, Golden C, Saadat H, Kain Z. Perfectionism as a predictor of physician burnout. BMC Health Services Research 2022, 22: 1425. PMID: 36443726, PMCID: PMC9703407, DOI: 10.1186/s12913-022-08785-7.Peer-Reviewed Original ResearchConceptsMethodsThis cross-sectional studyPhysician burnoutCross-sectional studyPhysician healthPatient carePhysiciansMaslach Burnout InventoryIndividual-level factorsLinear regression modelsBurnout InventoryCurrent findingsRegression modelsRecent editorialDetrimental effectsPersonal accomplishment burnoutEmotional exhaustion burnoutDepersonalization burnoutBurnoutEmotional exhaustionBackgroundBurnoutSelf-critical perfectionismRecurrent SARS-CoV-2 Serology Testing and Pandemic Anxiety: A Study of Pediatric Healthcare Workers
Li N, Martin SR, Heyming TW, Knudsen-Robbins C, Sanger T, Kain ZN. Recurrent SARS-CoV-2 Serology Testing and Pandemic Anxiety: A Study of Pediatric Healthcare Workers. International Journal Of Environmental Research And Public Health 2022, 19: 9562. PMID: 35954913, PMCID: PMC9368345, DOI: 10.3390/ijerph19159562.Peer-Reviewed Original ResearchConceptsPediatric healthcare workersSARS-CoV-2 antibodiesHealthcare workersSerology testingCOVID-19 anxietyPandemic-related anxietySARS-CoV-2 serology testingMeaningful decreaseSARS-CoV-2 testingVisual analog scaleLongitudinal cohort studyLogistic regression analysisPositive test resultsCohort studyAnalog scaleStudy baselineBivariate analysisMeasures analysisSelf-reported anxietyYears of experienceRegression analysisAnxietyAntibodiesPandemic anxietyHelpful strategies
2002
Music and preoperative anxiety: a randomized, controlled study.
Wang S, Kulkarni L, Dolev J, Kain Z. Music and preoperative anxiety: a randomized, controlled study. Anesthesia & Analgesia 2002, 94: 1489-94, table of contents. PMID: 12032013, DOI: 10.1097/00000539-200206000-00021.Peer-Reviewed Original Research
2001
The Use of Auricular Acupuncture to Reduce Preoperative Anxiety
Wang S, Peloquin C, Kain Z. The Use of Auricular Acupuncture to Reduce Preoperative Anxiety. Anesthesia & Analgesia 2001, 93: 1178-1180. PMID: 11682391, DOI: 10.1097/00000539-200111000-00024.Peer-Reviewed Original ResearchSensory Stimuli and Anxiety in Children Undergoing Surgery: A Randomized, Controlled Trial
Kain Z, Wang S, Mayes L, Krivutza D, Teague B. Sensory Stimuli and Anxiety in Children Undergoing Surgery: A Randomized, Controlled Trial. Anesthesia & Analgesia 2001, 92: 897-903. PMID: 11273921, DOI: 10.1097/00000539-200104000-00018.Peer-Reviewed Original ResearchConceptsInduction of anesthesiaChildren Undergoing SurgeryPostoperative day 1Postoperative behavioral changesSensory stimuliPost Hospitalization Behavior QuestionnaireUndergoing surgeryBehavioral recoveryIncreased complianceStimulation groupDay 1AnesthesiaControl groupAnesthesia maskOperating room lightsSurgeryAnxiety of childrenBehavioral interventionsOperating roomChildrenBehavioral changesExhibit low levelsBehavior QuestionnaireInductionAnxietyPreoperative Anxiolysis and Postoperative Recovery in Women Undergoing Abdominal Hysterectomy
Kain Z, Sevarino F, Rinder C, Pincus S, Alexander G, Ivy M, Heninger G. Preoperative Anxiolysis and Postoperative Recovery in Women Undergoing Abdominal Hysterectomy. Anesthesiology 2001, 94: 415-422. PMID: 11374599, DOI: 10.1097/00000542-200103000-00009.Peer-Reviewed Original ResearchConceptsMorning of surgeryAbdominal hysterectomyPostoperative painAnalgesia useTreatment groupsGroup differencesLate postoperative time pointsPatient-controlled analgesia consumptionSelf-reported postoperative painPatient-controlled analgesia usePostoperative clinical courseTime pointsPostoperative time pointsMillions of patientsMinimal beneficial effectsLittle objective dataAnalgesic consumptionRecovery parametersAnalgesia consumptionIntramuscular midazolamPostoperative outcomesPostoperative periodPostoperative recoveryAbdominal surgeryClinical courseAuricular acupuncture: a potential treatment for anxiety.
Wang S, Kain Z. Auricular acupuncture: a potential treatment for anxiety. Anesthesia & Analgesia 2001, 92: 548-53. PMID: 11159266, DOI: 10.1097/00000539-200102000-00049.Peer-Reviewed Original Research
2000
Preoperative anxiety and postoperative pain in women undergoing hysterectomy A repeated-measures design
Kain Z, Sevarino F, Alexander G, Pincus S, Mayes L. Preoperative anxiety and postoperative pain in women undergoing hysterectomy A repeated-measures design. Journal Of Psychosomatic Research 2000, 49: 417-422. PMID: 11182434, DOI: 10.1016/s0022-3999(00)00189-6.Peer-Reviewed Original ResearchConceptsPostoperative pain responsePreoperative state anxietyPostoperative painPreoperative anxietyPain responseElective abdominal hysterectomyImmediate postoperative painPostoperative pain managementState anxietyAnalgesic consumptionAbdominal hysterectomyPositive predictorPerioperative periodPain managementSurgical managementMultiple time pointsPainRepeated-measures designTime pointsStudy sampleHysterectomySignificant positive predictorPerceived stressWardsAnxietySocial adaptability, cognitive abilities, and other predictors for children’s reactions to surgery
Kain Z, Mayes L, Weisman S, Hofstadter M. Social adaptability, cognitive abilities, and other predictors for children’s reactions to surgery. Journal Of Clinical Anesthesia 2000, 12: 549-554. PMID: 11137417, DOI: 10.1016/s0952-8180(00)00214-2.Peer-Reviewed Original ResearchConceptsCognitive abilitiesSocial adaptabilityParental anxietyPerioperative anxietyGroup of childrenChild temperamentChildren's reactionsAnxious parentsCorrelational analysisParental stateAdaptive behaviorPersonality characteristicsHigh intelligenceAnxietyAge 3TemperamentChildrenStylePredictorsSurgical childrenPersonalityAbilityRegression analysisHigh levelsIntelligenceMidazolam: Effects on Amnesia and Anxiety in Children
Kain Z, Hofstadter M, Mayes L, Krivutza D, Alexander G, Wang S, Reznick J. Midazolam: Effects on Amnesia and Anxiety in Children. Anesthesiology 2000, 93: 676. PMID: 10969300, DOI: 10.1097/00000542-200009000-00016.Peer-Reviewed Original ResearchConceptsOral midazolamMidazolam administrationAnterograde amnesiaGood anterograde amnesiaSignificant anterograde amnesiaInduction of anesthesiaSignificant anxiolytic effectMidazolam groupGeneral anesthesiaSignificant group differencesAnxiolytic effectsBusy operating roomSurgical proceduresPostintervention testingDrug AdministrationControl groupMidazolamBaseline testingAnxiety measurement toolAnxiety of childrenOperating roomAdministrationGroup differencesPicture cardsAnesthesiaAttenuation of the Preoperative Stress Response with Midazolam
Kain Z, Sevarino F, Pincus S, Alexander G, Wang S, Ayoub C, Kosarussavadi B. Attenuation of the Preoperative Stress Response with Midazolam. Anesthesiology 2000, 93: 141-147. PMID: 10861157, DOI: 10.1097/00000542-200007000-00024.Peer-Reviewed Original ResearchConceptsPlacebo groupTreatment groupsPostoperative anxietyPreoperative sedativesPreoperative stress responsePlacebo-controlled trialFirst postoperative weekGreater reductionGlobal health indexAnalgesic consumptionIbuprofen usePlacebo injectionsPostoperative painClinical recoveryIntramuscular midazolamSurgery lengthPain recoveryPostoperative weekAnesthetic techniqueGeneral anesthesiaOutpatient surgeryPreoperative outcomesClinical significanceMidazolamSurgeryParental Presence and a Sedative Premedicant for Children Undergoing Surgery
Kain Z, Mayes L, Wang S, Caramico L, Krivutza D, Hofstadter M. Parental Presence and a Sedative Premedicant for Children Undergoing Surgery. Anesthesiology 2000, 92: 939-946. PMID: 10754612, DOI: 10.1097/00000542-200004000-00010.Peer-Reviewed Original ResearchConceptsPPIA groupSedative groupOverall careParental presenceParental satisfactionOperating roomParental anxietyInduction of anesthesiaPrimary endpointSecondary endpointsPerioperative periodOral midazolamOral sedativesPreoperative anxietySedative premedicantsAnesthesia maskChildrenSedativesAnxietyAdditive effectChild anxietyEndpointCareStandardized measuresInterventionPreoperative Anxiety and Postoperative Nausea and Vomiting in Children: Is There an Association?
Wang S, Kain Z. Preoperative Anxiety and Postoperative Nausea and Vomiting in Children: Is There an Association? Anesthesia & Analgesia 2000, 90: 571-575. PMID: 10702439, DOI: 10.1097/00000539-200003000-00014.Peer-Reviewed Original ResearchConceptsPostanesthesia care unitPostoperative nauseaPreoperative holding areaPreoperative anxietyOpioid consumptionPredictive valueMultivariate logistic regression modelAbsence of PONVOccurrence of PONVPerioperative opioid consumptionIncidence of nauseaOccurrence of nauseaAbsence of vomitingInduction of anesthesiaCross-sectional studyLogistic regression modelsChild anxietyHolding areaCare unitGeneral anesthesiaOutpatient surgeryPotential confoundersUnivariate analysisNauseaVomiting
1999
Preoperative Anxiety and Intraoperative Anesthetic Requirements
Maranets I, Kain Z. Preoperative Anxiety and Intraoperative Anesthetic Requirements. Anesthesia & Analgesia 1999, 89: 1346. DOI: 10.1213/00000539-199912000-00003.Peer-Reviewed Original ResearchConceptsIntraoperative anesthetic requirementsMaintenance of anesthesiaAnesthetic requirementsPropofol dosesPreoperative anxietyBaseline anxietyHypnotic componentAnesthetic stateIntraoperative propofol requirementsLaparoscopic tubal ligationCross-sectional studyHigh baseline anxietyAnxiety levelsBispectral index monitorMore propofolAnesthetic regimenIndependent predictorsPropofol requirementsInitial doseTubal ligationLarge dosesPatientsState anxietyAnxious patientsAnesthesiaPreoperative anxiety and intraoperative anesthetic requirements.
Maranets I, Kain Z. Preoperative anxiety and intraoperative anesthetic requirements. Anesthesia & Analgesia 1999, 89: 1346-51. PMID: 10589606, DOI: 10.1097/00000539-199912000-00003.Peer-Reviewed Original ResearchConceptsIntraoperative anesthetic requirementsTrait anxietyMaintenance of anesthesiaAnesthetic requirementsAnxiety levelsLow trait anxietyPropofol doseHigh trait anxietyLaparoscopic tubal ligationIntraoperative propofol requirementsAnesthetic stateDoses of anestheticsCross-sectional studyTubal ligationInitial doseBaseline anxietyAnxious patientsHypnotic componentState anxietyLarger dosesAnxietyInduction doseBispectral index monitoringPatientsDoseLeptin and the Perioperative Neuroendocrinological Stress Response1
Kain Z, Zimolo Z, Heninger G. Leptin and the Perioperative Neuroendocrinological Stress Response1. The Journal Of Clinical Endocrinology & Metabolism 1999, 84: 2438-2442. PMID: 10404818, DOI: 10.1210/jcem.84.7.5850.Peer-Reviewed Original ResearchConceptsSurgical stressLeptin decreaseHigh-dose opioid techniqueCortisol increasePhase IHigh-dose fentanylSurgical stress responseTotal abdominal hysterectomyCardiac surgery patientsBaseline 2 hPossible adverse outcomesBaseline 24 hPhase IIAcute stress responseDose fentanylAbdominal hysterectomyPostoperative morbiditySurgery patientsHysterectomy patientsLeptin levelsAnesthetic techniqueAdverse outcomesAdrenocortical axisCardiac patientsNeuroendocrine hormonesDistress During the Induction of Anesthesia and Postoperative Behavioral Outcomes
Kain Z, Wang S, Mayes L, Caramico L, Hofstadter M. Distress During the Induction of Anesthesia and Postoperative Behavioral Outcomes. Anesthesia & Analgesia 1999, 88: 1042-1047.. DOI: 10.1213/00000539-199905000-00013.Peer-Reviewed Original ResearchAn alternative method to alleviate postoperative nausea and vomiting in children
Wang S, Hofstadter M, Kain Z. An alternative method to alleviate postoperative nausea and vomiting in children. Journal Of Clinical Anesthesia 1999, 11: 231-234. PMID: 10434220, DOI: 10.1016/s0952-8180(99)00035-5.Peer-Reviewed Original ResearchConceptsPostoperative nauseaGeneral anesthesiaTreatment groupsControl groupASA physical status IPediatric surgery centersPhysical status IElective outpatient surgeryVisual analog scaleChildren ages 6Intravenous ondansetronAntiemetic effectRescue therapyStatus IRecurrent nauseaAnalog scaleOutpatient surgerySurgery centersNauseaVomitingEffective treatmentTreatment sequenceAge 6SurgeryAnesthesiaDistress during the induction of anesthesia and postoperative behavioral outcomes.
Kain Z, Wang S, Mayes L, Caramico L, Hofstadter M. Distress during the induction of anesthesia and postoperative behavioral outcomes. Anesthesia & Analgesia 1999, 88: 1042-7. PMID: 10320165, DOI: 10.1097/00000539-199905000-00013.Peer-Reviewed Original Research
1998
Preoperative Preparation Programs in Children
Kain Z, Caramico L, Mayes L, Genevro J, Bornstein M, Hofstadter M. Preoperative Preparation Programs in Children. Anesthesia & Analgesia 1998, 87: 1249-1255.. DOI: 10.1213/00000539-199812000-00007.Peer-Reviewed Original Research