Remission and relapse in major depression: a two-year prospective follow-up study
Ramana R, Paykel ES, Cooper Z, Hayhurst H, Saxty M, Surtees PG. Remission and relapse in major depression: a two-year prospective follow-up study. Psychological Medicine 1995, 25: 1161-1170. PMID: 8637946, DOI: 10.1017/s0033291700033134.Peer-Reviewed Original ResearchConceptsTwo-year prospective followMajor depressive subjectsGreater initial severityProspective followLate recurrencePoor outcomeWorse outcomesInitial severityDepressive subjectsMajor depressionRemissionAdequate treatmentRelapseGreater severityMonthsLonger durationDepressionSeveritySubjectsOutcomesTreatmentRecurrenceCohortFollowIllness