DeepSurv: personalized treatment recommender system using a Cox proportional hazards deep neural network
Katzman JL, Shaham U, Cloninger A, Bates J, Jiang T, Kluger Y. DeepSurv: personalized treatment recommender system using a Cox proportional hazards deep neural network. BMC Medical Research Methodology 2018, 18: 24. PMID: 29482517, PMCID: PMC5828433, DOI: 10.1186/s12874-018-0482-1.Peer-Reviewed Original ResearchMeSH KeywordsAlgorithmsHumansKaplan-Meier EstimateNeural Networks, ComputerOutcome Assessment, Health CarePrecision MedicineProportional Hazards ModelsConceptsDeep neural networksPersonalized treatment recommendationsTreatment recommendationsNeural networkTreatment optionsPatient covariatesRecommender systemsSurvival methodsCox proportional hazards modelDifferent treatment optionsProportional hazards modelSurvival modelsExtensive feature engineeringIndividual treatment recommendationsPrior medical knowledgeSet of patientsLinear Cox proportional hazards modelsPatient characteristicsClinical studiesPatient featuresSurvival timeFeature engineeringHazards modelArt survival modelsTreatment effectiveness