2020
Cannabinoid Type 1 Receptor is Undetectable in Rodent and Primate Cerebral Neural Stem Cells but Participates in Radial Neuronal Migration
Morozov YM, Mackie K, Rakic P. Cannabinoid Type 1 Receptor is Undetectable in Rodent and Primate Cerebral Neural Stem Cells but Participates in Radial Neuronal Migration. International Journal Of Molecular Sciences 2020, 21: 8657. PMID: 33212822, PMCID: PMC7696736, DOI: 10.3390/ijms21228657.Peer-Reviewed Original ResearchConceptsNeural stem cellsStem cellsCannabinoid type 1 receptorType 1 receptorFate determinationRadial neuronal migrationCell movementEmbryonic developmentIntracellular vesiclesCellular locationMRNA sequencingMolecular mechanismsCortical plateElectron microscopic reconstructionCellular proliferationNeuronal migrationZone cellsSubventricular zone cellsEmbryonic miceMolecular substratesSVZ cellsMicroscopic reconstructionRecreational cannabis useMacaque cerebral cortexPrimate neurons
2016
Ultrastructural evidence for impaired mitochondrial fission in the aged rhesus monkey dorsolateral prefrontal cortex
Morozov YM, Datta D, Paspalas CD, Arnsten AF. Ultrastructural evidence for impaired mitochondrial fission in the aged rhesus monkey dorsolateral prefrontal cortex. Neurobiology Of Aging 2016, 51: 9-18. PMID: 28027494, PMCID: PMC5292282, DOI: 10.1016/j.neurobiolaging.2016.12.001.Peer-Reviewed Original Research
2015
Alteration of SLP2‐like immunolabeling in mitochondria signifies early cellular damage in developing and adult mouse brain
Morozov YM, Sun YY, Kuan CY, Rakic P. Alteration of SLP2‐like immunolabeling in mitochondria signifies early cellular damage in developing and adult mouse brain. European Journal Of Neuroscience 2015, 43: 245-257. PMID: 26547131, PMCID: PMC4784115, DOI: 10.1111/ejn.13124.Peer-Reviewed Original ResearchConceptsStomatin-like protein 2Inner mitochondrial membrane protein complexMitochondrial membrane protein complexesMembrane protein complexesInner mitochondrial membraneRegulated cell deathAmino acid sequenceLinear amino acid sequenceCellular damageProtein complexesMitochondrial matrixAdult mouse brainMitochondrial membraneAcid sequenceMitochondrial biogenesisMouse brainHuman diseasesAnti-CB1 antibodyCell deathMitochondriaMitochondrial dysfunctionNeuronal cellsProtein 2Normal mitochondriaSelective labeling