2017
Bisphenol-A exposure in utero programs a sexually dimorphic estrogenic state of hepatic metabolic gene expression
Ilagan Y, Mamillapalli R, Goetz L, Kayani J, Taylor HS. Bisphenol-A exposure in utero programs a sexually dimorphic estrogenic state of hepatic metabolic gene expression. Reproductive Toxicology 2017, 71: 84-94. PMID: 28476547, DOI: 10.1016/j.reprotox.2017.05.001.Peer-Reviewed Original ResearchConceptsBPA exposureGene expressionAdult gene expressionFetal BPA exposureBisphenol A (BPA) exposureMetabolic gene expressionEstrogen receptor alphaExpression of genesBeta gene expressionEstrogenic stateEstrogen treatmentPregnant miceMetabolic disordersE2 stimulationReceptor alphaFetal developmentLipid metabolismDay 9Developmental programmingSexual dimorphismFemale offspringLiverObesityGenesAdult responses
2014
Altered Genome-Wide Methylation in Endometriosis
Naqvi H, Ilagan Y, Krikun G, Taylor HS. Altered Genome-Wide Methylation in Endometriosis. Reproductive Sciences 2014, 21: 1237-1243. PMID: 24784717, PMCID: PMC5933183, DOI: 10.1177/1933719114532841.Peer-Reviewed Original ResearchConceptsGene expressionBone morphogenetic protein receptorGenome-wide methylationDual specificity phosphatase 22Morphogenetic protein receptorTumor protein 73Genome-wide methylation arrayAberrant DNA methylationInhibitor of DNADNA methylationCandidate genesBinding protein 7Member 21Methylation arraysProtein receptorsQuantitative real-time polymerase chain reactionGenesImmunoglobulin SuperfamilyAberrant methylationMethylation statusProtein 7MethylationCell proliferationAbnormal regulationReceptor 1B