Featured Publications
Genetic determinants for the racial disparities in the risk of prostate and testicular cancers
Uzamere I, Wang Y, Zheng T, Zhu Y. Genetic determinants for the racial disparities in the risk of prostate and testicular cancers. Communications Medicine 2022, 2: 138. PMID: 36352009, PMCID: PMC9630379, DOI: 10.1038/s43856-022-00205-5.Peer-Reviewed Original ResearchRisk of prostateTesticular cancerProstate cancerRisk allelesRacial disparitiesEuropean ancestryAfrican ancestryMethodsThe current studyLower incidenceIncidence disparitiesHigh incidenceRisk allele frequenciesCancerConclusionsOur findingsGenetic factorsMenT-testRegression analysisProstateIncidenceGenetic determinantsCurrent studyRiskAllele frequenciesDisparities
2007
Variants in circadian genes and prostate cancer risk: a population-based study in China
Chu LW, Zhu Y, Yu K, Zheng T, Yu H, Zhang Y, Sesterhenn I, Chokkalingam AP, Danforth KN, Shen MC, Stanczyk FZ, Gao YT, Hsing AW. Variants in circadian genes and prostate cancer risk: a population-based study in China. Prostate Cancer And Prostatic Diseases 2007, 11: 342-348. PMID: 17984998, DOI: 10.1038/sj.pcan.4501024.Peer-Reviewed Original ResearchConceptsProstate cancer riskLess insulin resistanceInsulin resistanceCancer riskGG genotypePopulation-based case-control studyGreater insulin resistancePopulation-based studyCase-control studyVariant C alleleCircadian genesProstate tumorigenesisC alleleNeed of confirmationMenRiskGenotypesVariantsGenes
2006
Does “Clock” Matter in Prostate Cancer?
Zhu Y, Zheng T, Stevens RG, Zhang Y, Boyle P. Does “Clock” Matter in Prostate Cancer? Cancer Epidemiology Biomarkers & Prevention 2006, 15: 3-5. PMID: 16434577, PMCID: PMC2366206, DOI: 10.1158/1055-9965.epi-05-0631.Peer-Reviewed Original ResearchConceptsProstate cancerSex hormone levelsFemale breast cancerCommon cancer typesEvening shift workHormone levelsPrognostic biomarkerBreast cancerAndrogen expressionProstate tumorigenesisCancerCancer typesShift workDaily biochemicalIndividual riskEtiologyCircadian rhythmGenetic variantsRiskCircadian clockCircadian cycleBiomarkersPhysiologicProfound effect
2005
Occupation and Risk of Pancreatic Cancer: A Population-Based Case–Control Study in Iowa
Zhang Y, Cantor KP, Lynch CF, Zhu Y, Zheng T. Occupation and Risk of Pancreatic Cancer: A Population-Based Case–Control Study in Iowa. Journal Of Occupational And Environmental Medicine 2005, 47: 392-398. PMID: 15824631, DOI: 10.1097/01.jom.0000158707.88801.f5.Peer-Reviewed Original Research