2021
TET1-mediated DNA hydroxymethylation regulates adult remyelination in mice
Moyon S, Frawley R, Marechal D, Huang D, Marshall-Phelps KLH, Kegel L, Bøstrand SMK, Sadowski B, Jiang YH, Lyons DA, Möbius W, Casaccia P. TET1-mediated DNA hydroxymethylation regulates adult remyelination in mice. Nature Communications 2021, 12: 3359. PMID: 34099715, PMCID: PMC8185117, DOI: 10.1038/s41467-021-23735-3.Peer-Reviewed Original ResearchConceptsDNA hydroxymethylationSolute carrier gene familyNeuro-glial communicationZebrafish mutantsGene familyTranscriptomic analysisMyelin interfaceTen-ElevenAdult central nervous systemCentral nervous systemTET1Overexpressing cellsAdult remyelinationExpression levelsMutantsHydroxymethylationGenesNervous systemRepairMyelin repairTransportersKnockoutMiceRegulationAged mice
2017
A Presynaptic Function of Shank Protein in Drosophila
Wu S, Gan G, Zhang Z, Sun J, Wang Q, Gao Z, Li M, Jin S, Huang J, Thomas U, Jiang YH, Li Y, Tian R, Zhang YQ. A Presynaptic Function of Shank Protein in Drosophila. Journal Of Neuroscience 2017, 37: 11592-11604. PMID: 29074576, PMCID: PMC6705749, DOI: 10.1523/jneurosci.0893-17.2017.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnimals, Genetically ModifiedDrosophilaFemaleMaleMushroom BodiesNerve Tissue ProteinsNeuromuscular JunctionPresynaptic TerminalsConceptsSynapse developmentMushroom bodiesPresynaptic functionHuman genetic studiesPostsynaptic densityPSD scaffold proteinsPeripheral neuromuscular junctionsNull mutantsMushroom body calyxScaffold proteinFamily genesFamily proteinsExpression analysisDevelopmental defectsShank proteinsGenetic studiesShank familyCalyx structureFunction mutationsOnly memberIdiopathic autism spectrum disorderSynaptic roleNovel insightsProteinDrosophila