Autism as a disorder of neural information processing: directions for research and targets for therapy
Belmonte MK, Cook EH, Anderson GM, Rubenstein JL, Greenough WT, Beckel-Mitchener A, Courchesne E, Boulanger LM, Powell SB, Levitt PR, Perry EK, Jiang YH, DeLorey TM, Tierney E. Autism as a disorder of neural information processing: directions for research and targets for therapy. Molecular Psychiatry 2004, 9: 646-663. PMID: 15037868, DOI: 10.1038/sj.mp.4001499.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderNormal developmental courseNeural information processingBrain developmentSpectrum disorderBehavioral findingsDevelopmental courseComplex behavioral syndromeNeural systemsInformation processingAutismBehavioral manipulationMultiple predisposing factorsDevelopmental pathCommon developmental pathNeural propertiesCausal factorsBehavioral syndromeAbnormal brain developmentDevelopmental processesCognitionActivity-dependent developmentDisordersComplex waysEndophenotypes