Bayesian network-driven clustering analysis with feature selection for high-dimensional multi-modal molecular data
Zhao Y, Chang C, Hannum M, Lee J, Shen R. Bayesian network-driven clustering analysis with feature selection for high-dimensional multi-modal molecular data. Scientific Reports 2021, 11: 5146. PMID: 33664338, PMCID: PMC7933297, DOI: 10.1038/s41598-021-84514-0.Peer-Reviewed Original ResearchConceptsMolecular dataJoint posterior distributionHigh-dimensional settingsVariational Bayes approachSingle-cell dataArt clustering methodsPosterior distributionMolecular profiling dataComputational efficiencyCanonical oncogenicTranscriptomic alterationsBiological discoveryModel inferenceBayes approachCell decompositionStemness phenotypeProfiling dataSingle cellsComputational methodsBulk tumorPathway alterationsNebulaClustering methodAnalysis settingsCell data