Analysis of blood-induced Anopheles gambiae midgut proteins and sexual stage Plasmodium falciparum interaction reveals mosquito genes important for malaria transmission
Cui Y, Niu G, Li VL, Wang X, Li J. Analysis of blood-induced Anopheles gambiae midgut proteins and sexual stage Plasmodium falciparum interaction reveals mosquito genes important for malaria transmission. Scientific Reports 2020, 10: 14316. PMID: 32868841, PMCID: PMC7459308, DOI: 10.1038/s41598-020-71186-5.Peer-Reviewed Original ResearchConceptsMidgut proteinsCandidate genesStage parasitesGene expression profilesMosquito genesUnique genesMalaria transmissionInsect cellsMosquito proteinsSexual stage parasitesGene productsAsexual stage parasitesKnockdown assaysP. falciparum invasionProtein sequencesPlasmodium invasionAnopheles gambiaeSecretory proteinsExpression profilesMosquito midgutParasite invasionGenesCell lysatesMosquito susceptibilityProtein