2024
A cell atlas of the adult female Aedes aegypti midgut revealed by single-cell RNA sequencing
Wang S, Huang Y, Wang F, Han Q, Ren N, Wang X, Cui Y, Yuan Z, Xia H. A cell atlas of the adult female Aedes aegypti midgut revealed by single-cell RNA sequencing. Scientific Data 2024, 11: 587. PMID: 38839790, PMCID: PMC11153528, DOI: 10.1038/s41597-024-03432-8.Peer-Reviewed Original ResearchConceptsSingle-cell RNA sequencingFat body cellsRNA sequencingSingle-cell levelHemocyte cellsEnteroendocrine cellsVisceral musclesSingle-nucleus resolutionTranscriptome of AeMosquito midgutAedes aegypti midgutMidgut transcriptomeBlood meal digestionCell atlasCardia cellsArbovirus infectionMeal digestionNutrient absorptionMidgut cellsMidgutBody cellsCell clustersPrimary vectorSequenceCells
2022
Cellular diversity and gene expression profiles in the male and female brain of Aedes aegypti
Cui Y, Behura SK, Franz AWE. Cellular diversity and gene expression profiles in the male and female brain of Aedes aegypti. BMC Genomics 2022, 23: 119. PMID: 35144549, PMCID: PMC8832747, DOI: 10.1186/s12864-022-08327-9.Peer-Reviewed Original ResearchConceptsFemale brainMedulla neuronsCell clustersDimorphic behaviorsCell typesBrain cell typesSingle-nucleus RNA sequencingMonoaminergic neuronsProjection neuronsMosquito brainMale brainNeuronsKenyon cellsBrainYellow feverCell atlasCellular compositionGene expression profilesFemale mosquitoesGliaMosquito vectorsType compositionType proportionsRNA sequencingAdult males