2021
Diagnostic accuracy of stress-only myocardial perfusion SPECT improved by deep learning
Liu H, Wu J, Miller EJ, Liu C, Yaqiang, Liu, Liu YH. Diagnostic accuracy of stress-only myocardial perfusion SPECT improved by deep learning. European Journal Of Nuclear Medicine And Molecular Imaging 2021, 48: 2793-2800. PMID: 33511425, DOI: 10.1007/s00259-021-05202-9.Peer-Reviewed Original ResearchConceptsMyocardial perfusion imagingCoronary artery diseaseMyocardial perfusion abnormalitiesPerfusion abnormalitiesDiagnostic accuracyConvolutional neural networkTomography myocardial perfusion imagingYale-New Haven HospitalMyocardial perfusion defect sizeSPECT myocardial perfusion imagingAbnormal myocardial perfusionReceiver-operating characteristic curvePerfusion defect sizeNew Haven HospitalAUC valuesSingle photon emissionMyocardial perfusion SPECTDeep learningHigh diagnostic accuracyArtery diseaseDL methodsFinal diagnosisPatient genderMyocardial perfusionPerfusion SPECT
2018
New Method for Quantification of the Left Ventricular Function from Low-dose Equilibrium Radionuclide Angiocardiography: Comparisons with Conventional Methods in Patients
Liu Y, Tsatkin V, Fazzone-Chettiar R, Miller E, Sinusas A. New Method for Quantification of the Left Ventricular Function from Low-dose Equilibrium Radionuclide Angiocardiography: Comparisons with Conventional Methods in Patients. 2018, 00: 1-3. DOI: 10.1109/nssmic.2018.8824749.Peer-Reviewed Original ResearchEnd-diastolic volumeEquilibrium radionuclide angiocardiographyLeft ventricular functionGated blood pool SPECTPeak filling rateBlood pool SPECTEjection fractionVentricular functionRadionuclide angiocardiographyLV end-diastolic volumeHigh-dose injectionLow-dose injectionsAnterior oblique viewSingle photon emissionRed blood cellsDose reductionReduced radiation dosePatientsShort-axis slicesBlood cellsRadiation exposureGold standardImaging modalitiesRadiation doseOblique view
2010
Recent Progress on SPECT Imaging with Near-field Coded Aperture Collimation: A Small Animal Study
Mu Z, Dobrucki W, Hu X, Liu Y. Recent Progress on SPECT Imaging with Near-field Coded Aperture Collimation: A Small Animal Study. 2010, 3450-3453. DOI: 10.1109/nssmic.2010.5874447.Peer-Reviewed Original ResearchAnimal studiesOpen chest surgeryMyocardial perfusion defectsLeft ventricular myocardiumThree-dimensional single photon emissionSingle photon emissionVivo rat heartsPermanent myocardial infarctionCoronary arteryMyocardial infarctionSmall animal studiesPerfusion defectsJugular veinSurgical proceduresRadiotracer injectionVentricular myocardiumRat heartRatsLVAnimal imaging systemAnterior regionSmall animal imaging systemSPECTPhoton emissionSPECT technology
1999
Quantification of regional myocardial wall thickening on electrocardiogram-gated SPECT imaging
Shen M, Liu Y, Sinusas A, Fetterman R, Bruni W, Drozhinin O, Zaret B, Wackers F. Quantification of regional myocardial wall thickening on electrocardiogram-gated SPECT imaging. Journal Of Nuclear Cardiology 1999, 6: 583-595. PMID: 10608585, DOI: 10.1016/s1071-3581(99)90095-8.Peer-Reviewed Original ResearchMeSH KeywordsAlgorithmsComputer SimulationDiastoleElectrocardiographyHeart VentriclesHumansImage Processing, Computer-AssistedModels, CardiovascularMyocardial InfarctionObserver VariationPhantoms, ImagingPilot ProjectsRadiopharmaceuticalsReproducibility of ResultsSoftwareSystoleTechnetium Tc 99m SestamibiTomography, Emission-Computed, Single-PhotonVentricular Function, LeftVentricular RemodelingVentriculography, First-PassConceptsPrior myocardial infarctionRegional wall thickeningNormal subjectsMyocardial infarctionWall thickeningNormal wall thickeningPilot studyRegional left ventricular functionLeft ventricular functionAbnormal wall thickeningPercent count increaseECG-gated SPECT imagesSingle photon emissionSPECT imagesCardiac cycleLeft ventricular wallReproducibility of interpretationRegional left ventricular wallPrior infarctionCoronary diseaseVentricular functionValidation studyInfarct areaNormal rangeAnatomic areas
1996
Quantification of technetium 99m-labeled sestamibi single-photon emission computed tomography based on mean counts improves accuracy for assessment of relative regional myocardial blood flow: Experimental validation in a canine model
Liu Y, Sinusas A, Shi C, Shen M, Dione D, Heller E, Wackers F. Quantification of technetium 99m-labeled sestamibi single-photon emission computed tomography based on mean counts improves accuracy for assessment of relative regional myocardial blood flow: Experimental validation in a canine model. Journal Of Nuclear Cardiology 1996, 3: 312-320. PMID: 8799250, DOI: 10.1016/s1071-3581(96)90091-4.Peer-Reviewed Original ResearchConceptsMyocardial blood flowRelative blood flowRelative myocardial blood flowRegional myocardial blood flowCoronary artery occlusionBlood flowSingle photon emissionArtery occlusionCanine modelShort-axis slicesEx vivoSestamibi single-photon emissionMyocardial countsFlow deficitsMyocardial count densityNormal blood flowMean countsRegional myocardial perfusionCount profilesMIBI uptakeMIBI SPECTSestamibi SPECTMyocardial perfusionCircumferential count profilesRelative regional myocardial blood flow