Development of Small Diameter Nanofiber Tissue Engineered Arterial Grafts
Kurobe H, Maxfield MW, Tara S, Rocco KA, Bagi PS, Yi T, Udelsman B, Zhuang ZW, Cleary M, Iwakiri Y, Breuer CK, Shinoka T. Development of Small Diameter Nanofiber Tissue Engineered Arterial Grafts. PLOS ONE 2015, 10: e0120328. PMID: 25830942, PMCID: PMC4382213, DOI: 10.1371/journal.pone.0120328.Peer-Reviewed Original ResearchConceptsSmooth muscle cellsSmall-diameter arteriesSynthetic graftsDiameter arteriesSurvival of miceLarge-sized arteriesF4/80-positive macrophagesInner luminal diameterMatrix metalloproteinases 2Smooth muscle actinAneurysmal dilatationGraft stenosisSurgical repairPatency ratesSham groupArterial graftsSized arteriesVascular diseaseSham operationBg miceLuminal diameterDoppler ultrasoundHistologic analysisInterposition conduitsMuscle actin