A novel predictive model incorporating immune-related gene signatures for overall survival in melanoma patients
Liao M, Zeng F, Li Y, Gao Q, Yin M, Deng G, Chen X. A novel predictive model incorporating immune-related gene signatures for overall survival in melanoma patients. Scientific Reports 2020, 10: 12462. PMID: 32719391, PMCID: PMC7385638, DOI: 10.1038/s41598-020-69330-2.Peer-Reviewed Original ResearchMeSH KeywordsBeta-DefensinsBiomarkers, TumorChemokine CCL8HumansMelanomaNomogramsPrognosisSurvival AnalysisTranscriptomeConceptsImmune-related genesMelanoma patientsGene Expression Omnibus databaseImmune-related gene signatureConventional staging systemsLow-risk patientsIndependent prognostic factorDecision curve analysisCancer Genome Atlas (TCGA) databaseTwo-gene signatureSignature gene expressionIRG signatureOverall survivalPrognostic factorsClinical parametersPrediction nomogramStaging systemTNM stagePatient prognosisConcordance indexPrognostic performanceIndividual prognosisInvasive typeSkin cancerImmune system