2021
Data-independent acquisition-based proteome and phosphoproteome profiling across six melanoma cell lines reveals determinants of proteotypes
Gao E, Li W, Wu C, Shao W, Di Y, Liu Y. Data-independent acquisition-based proteome and phosphoproteome profiling across six melanoma cell lines reveals determinants of proteotypes. Molecular Omics 2021, 17: 413-425. PMID: 33728422, PMCID: PMC8205956, DOI: 10.1039/d0mo00188k.Peer-Reviewed Original Research
2020
SECAT: Quantifying Protein Complex Dynamics across Cell States by Network-Centric Analysis of SEC-SWATH-MS Profiles
Rosenberger G, Heusel M, Bludau I, Collins BC, Martelli C, Williams EG, Xue P, Liu Y, Aebersold R, Califano A. SECAT: Quantifying Protein Complex Dynamics across Cell States by Network-Centric Analysis of SEC-SWATH-MS Profiles. Cell Systems 2020, 11: 589-607.e8. PMID: 33333029, PMCID: PMC8034988, DOI: 10.1016/j.cels.2020.11.006.Peer-Reviewed Original ResearchConceptsProtein-protein interactionsProtein complexesCell statesProtein complex dynamicsNative protein complexesMacromolecular complex formationPaper's transparent peer review processProtein interaction networksSEC-SWATHMultiple cell statesNetwork-centric analysisCellular processesInteraction networksMass spectrometric data analysisProteome OrganizationMolecular mechanismsRegulatory roleMass spectrometric analysisNetwork-based studyMultiplexed characterizationComplex formationSpectrometric data analysisSpectrometric analysisAlgorithmic toolkitState-specific changes