2021
Testing for treatment effect in covariate-adaptive randomized trials with generalized linear models and omitted covariates
Li Y, Ma W, Qin Y, Hu F. Testing for treatment effect in covariate-adaptive randomized trials with generalized linear models and omitted covariates. Statistical Methods In Medical Research 2021, 30: 2148-2164. PMID: 33899607, DOI: 10.1177/09622802211008206.Peer-Reviewed Original ResearchConceptsCovariate-adaptive randomizationCovariate-adaptive randomization methodsCovariate-adaptive randomized trialsValidity of statistical inferenceInflated type I errorLinear modelType I errorGeneralized linear modelAsymptotic distributionProposed adjustment methodAsymptotic resultsInferential propertiesTest statisticsAnti-conservativeStatistical inferenceContinuous responseUnadjusted testsNull hypothesisTheoretical findingsTreatment effectsInvalid testsRandomization methodNumerical studyCovariatesAdjustment method
2019
Statistical Inference for Covariate-Adaptive Randomization Procedures
Ma W, Qin Y, Li Y, Hu F. Statistical Inference for Covariate-Adaptive Randomization Procedures. Journal Of The American Statistical Association 2019, 115: 1488-1497. DOI: 10.1080/01621459.2019.1635483.Peer-Reviewed Original ResearchCovariate-adaptive randomizationCovariate-adaptiveCovariate-adaptive randomization proceduresProperties of statistical methodsTheoretical resultsRandomization procedureLinear model frameworkAsymptotic representationCoin designTheoretical propertiesStatistical inferenceCovariate informationSimulation studySequential randomizationCovariate balanceInference propertiesSupplementary materialsComplete randomizationGeneral theoryBalanced treatment groupsCovariatesInferenceStatistical methodsRerandomizationRandomization