Endothelial Expression of Beta‐1 Integrin Is Required for Embryonic Vascular Patterning and Postnatal Vascular Remodeling
lei L, Liu D, Huang Y, Jovin I, Shai S, Kyriakides T, Ross R, Giordano F. Endothelial Expression of Beta‐1 Integrin Is Required for Embryonic Vascular Patterning and Postnatal Vascular Remodeling. The FASEB Journal 2008, 22: 1122.11-1122.11. DOI: 10.1096/fasebj.22.1_supplement.1122.11.Peer-Reviewed Original ResearchVascular remodelingEndothelial expressionSevere fetal growth retardationFetal growth retardationCre/loxP techniqueAbnormal vascular remodelingSignificant clinical importancePostnatal vascular remodelingΒ1 subunit expressionΒ1 integrinBeta 1 integrinΒ1 integrin expressionBlood flowAdult miceClinical importanceSubunit expressionGlobal deletionPostnatal survivalGrowth retardationEndothelial cellsIntegrin expressionTime pointsHealing woundsSignificant functional effectsFunctional effects