2023
Colorectal Carcinoma With Sarcomatoid Components
Golconda U, McHugh K, Allende D, Collins K, Henn P, Lacambra M, Bejarano P, Groisman G, Loughrey M, Monappa V, Zhang X, Hornick J, Gonzalez R. Colorectal Carcinoma With Sarcomatoid Components. The American Journal Of Surgical Pathology 2023, 48: 465-474. PMID: 38155543, DOI: 10.1097/pas.0000000000002172.Peer-Reviewed Original ResearchMeSH KeywordsAgedCarcinomaCarcinosarcomaColorectal NeoplasmsDNA HelicasesFemaleHumansMaleNuclear ProteinsSarcomaTranscription FactorsConceptsSarcomatoid componentColorectal carcinomaUndifferentiated carcinomaTumor-infiltrating lymphocytesNodal metastasisAbdominal painDistant metastasisRare subtypeSMARCA4 lossTumor buddingHeterologous elementsRepair protein expressionRectosigmoid regionSpindle cellsGastrointestinal bleedingKeratin-positivePoor prognosisFollow-upCarcinomaMismatch repair protein expressionMolecular testingAdvanced stageTumorLoss of mismatch repair protein expressionProtein expression
2021
Clinicopathological significance of neutrophil-rich colorectal carcinoma
Rottmann BG, Patel N, Ahmed M, Deng Y, Ciarleglio M, Vyas M, Jain D, Zhang X. Clinicopathological significance of neutrophil-rich colorectal carcinoma. Journal Of Clinical Pathology 2021, 76: 34-39. PMID: 34312298, PMCID: PMC10910606, DOI: 10.1136/jclinpath-2021-207702.Peer-Reviewed Original ResearchMeSH KeywordsColorectal NeoplasmsDNA Mismatch RepairHumansNeoplastic Syndromes, HereditaryNeutrophilsPrognosisConceptsRecurrence-free survivalColorectal carcinomaHistological gradeTumor locationRight-sided tumor locationTumor cellsDNA mismatch repair (MMR) statusIndependent risk factorKaplan-Meier analysisHigh histological gradeAdvanced TNM stageMismatch repair statusPrognostic significanceCRC casesClinicopathological significanceTNM stageMetastasis stagePatient prognosisRisk factorsClinicopathological parametersMultivariate analysisRepair statusPatientsCarcinomaHigh rateThe prospective on molecular diagnostics of colorectal cancer and its clinical implications
Liang Y, Shi X, Zhang X, Zhang L. The prospective on molecular diagnostics of colorectal cancer and its clinical implications. 中华病理学杂志 2021, 50: 66-68. PMID: 33396991, DOI: 10.3760/cma.j.cn112151-20201120-00856.Peer-Reviewed Original Research
2019
Adverse Histologic Features in Colorectal Nonpedunculated Malignant Polyps With Nodal Metastasis
Patel N, Vyas M, Celli R, Jain D, Zhang X. Adverse Histologic Features in Colorectal Nonpedunculated Malignant Polyps With Nodal Metastasis. The American Journal Of Surgical Pathology 2019, 44: 241-246. PMID: 31498179, DOI: 10.1097/pas.0000000000001369.Peer-Reviewed Original ResearchConceptsHigh-grade tumor buddingAdverse histologic featuresMalignant polypsNodal metastasisTumor buddingHistologic featuresLymphovascular invasionNode metastasisLymph node metastatic potentialMargin statusSubsequent resectionColectomy specimenColectomy proceduresDifferentiated clustersTumor differentiationOdds ratioRisk featuresMetastasisMetastatic potentialPiecemeal polypectomyPolypsRiskInvasionColectomyResection
2015
Interval colorectal carcinoma: An unsolved debate
Benedict M, Galvao Neto A, Zhang X. Interval colorectal carcinoma: An unsolved debate. World Journal Of Gastroenterology 2015, 21: 12735-12741. PMID: 26668498, PMCID: PMC4671029, DOI: 10.3748/wjg.v21.i45.12735.Peer-Reviewed Original ResearchMeSH KeywordsAdenomatous PolypsCarcinomaColonic PolypsColorectal NeoplasmsHumansIncidencePredictive Value of TestsPrognosisRisk AssessmentRisk FactorsConceptsInterval colorectal carcinomasColorectal carcinomaNegative screening testNew cancer diagnosesHigh-risk individualsPolypoid neoplasiasExcised lesionsGastrointestinal neoplasiaCommunity hospitalRisk individualsSignificant health riskScreening testMultifactorial natureCancer diagnosisNeoplasiaHealth risksUnsolved debatePatientsCarcinomaHospitalLesionsEndoscopistsDiseaseDiagnosis