Collapsing-based and kernel-based single-gene analyses applied to Genetic Analysis Workshop 17 mini-exome data
Li L, Zheng W, Lee JS, Zhang X, Ferguson J, Yan X, Zhao H. Collapsing-based and kernel-based single-gene analyses applied to Genetic Analysis Workshop 17 mini-exome data. BMC Proceedings 2011, 5: s117. PMID: 22373309, PMCID: PMC3287841, DOI: 10.1186/1753-6561-5-s9-s117.Peer-Reviewed Original ResearchMinor allele frequencyCausal variantsGenetic Analysis Workshop 17 mini-exome dataSingle gene analysisLow minor allele frequencyGAW17 data setRare variantsFalse positive genesFunctional annotationPhenotypic varianceTop genesGenotypic dataNoncausal variantsAssociation dataGenetic effectsAssociation TestUnrelated individualsAllele frequenciesGenesSame genotype distributionBayesian mixed-effects modelsVariantsSimilar genotype distributionGAW17Traits