2024
Skin Transcriptomics Are Associated With Lung Function Impairment and Specific Cell Type Enrichment in Systemic Sclerosis-related Interstitial Lung Disease
Zielonka J, Li N, Wang Z, Yan X, Ryu C, Gomez J. Skin Transcriptomics Are Associated With Lung Function Impairment and Specific Cell Type Enrichment in Systemic Sclerosis-related Interstitial Lung Disease. 2024, a4905-a4905. DOI: 10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a4905.Peer-Reviewed Original Research
2023
Skin Transcriptomes Are Associated With Lung Function Impairment in Systemic Sclerosis Related Interstitial Lung Disease
Zielonka J, Li N, Wang Z, Yan X, Gomez J. Skin Transcriptomes Are Associated With Lung Function Impairment in Systemic Sclerosis Related Interstitial Lung Disease. 2023, a2221-a2221. DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a2221.Peer-Reviewed Original Research
2020
A Network of Sputum MicroRNAs is Associated with Neutrophilic Airway Inflammation in Asthma
Gomez JL, Chen A, Diaz MP, Zirn N, Gupta A, Britto C, Sauler M, Yan X, Stewart E, Santerian K, Grant N, Liu Q, Fry R, Rager J, Cohn L, Alexis N, Chupp GL. A Network of Sputum MicroRNAs is Associated with Neutrophilic Airway Inflammation in Asthma. American Journal Of Respiratory And Critical Care Medicine 2020, 0: 51-64. PMID: 32255668, PMCID: PMC7328332, DOI: 10.1164/rccm.201912-2360oc.Peer-Reviewed Original ResearchConceptsEndoplasmic reticulum stressAirway inflammationNeutrophil countClinical featuresT-helper cell type 17Neutrophilic airway inflammationReticulum stressSputum of subjectsLung function impairmentHistory of hospitalizationNumber of neutrophilsPeripheral blood neutrophilsSputum of patientsMicroRNA expressionAsthma severityTh17 pathwayFunction impairmentAirway samplesMicroRNA networkBlood neutrophilsOzone exposureAsthmaSputumCellular sourceClinical phenotype