Cooperation between MyD88 and TRIF pathways in TLR synergy via IRF5 activation
Ouyang X, Negishi H, Takeda R, Fujita Y, Taniguchi T, Honda K. Cooperation between MyD88 and TRIF pathways in TLR synergy via IRF5 activation. Biochemical And Biophysical Research Communications 2007, 354: 1045-1051. PMID: 17275788, DOI: 10.1016/j.bbrc.2007.01.090.Peer-Reviewed Original ResearchConceptsToll-like receptorsInterferon regulatory factor 5TLR synergyTRIF pathwayImmune systemMultiple Toll-like receptorsTranscription factor interferon regulatory factor 5Regulatory factor 5Agonist combinationsImmune cellsMyD88 adaptorInnate immunityIRF5 activationTRIF adaptorMyD88Synergistic inductionActivationFactor 5Target genesCross talkCellsAgonistsTRIFPathwayImmunity