2020
KTN1 variants and risk for attention deficit hyperactivity disorder
Luo X, Guo X, Tan Y, Zhang Y, Garcia‐Milian R, Wang Z, Shi J, Yu T, Ji J, Wang X, Xu J, Zhang H, Zuo L, Lu L, Wang K, Li C. KTN1 variants and risk for attention deficit hyperactivity disorder. American Journal Of Medical Genetics Part B Neuropsychiatric Genetics 2020, 183: 234-244. PMID: 32190980, PMCID: PMC7210069, DOI: 10.1002/ajmg.b.32782.Peer-Reviewed Original Research
2016
SNHG8 is identified as a key regulator of epstein-barr virus(EBV)-associated gastric cancer by an integrative analysis of lncRNA and mRNA expression
Huang T, Ji Y, Hu D, Chen B, Zhang H, Li C, Chen G, Luo X, Zheng XW, Lin X. SNHG8 is identified as a key regulator of epstein-barr virus(EBV)-associated gastric cancer by an integrative analysis of lncRNA and mRNA expression. Oncotarget 2016, 5: 80990-81002. PMID: 27835598, PMCID: PMC5348371, DOI: 10.18632/oncotarget.13167.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedCell Transformation, ViralComputational BiologyDatabases, GeneticEpstein-Barr Virus InfectionsFemaleGene Expression ProfilingGene Expression Regulation, NeoplasticGene Regulatory NetworksHerpesvirus 4, HumanHost-Pathogen InteractionsHumansMaleMiddle AgedReal-Time Polymerase Chain ReactionRNA, Long NoncodingRNA, MessengerRNA, NeoplasmSequence Analysis, RNAStomach NeoplasmsYoung AdultConceptsEpstein-Barr virusGastric cancerAdjacent normal tissuesGastric carcinomaNormal tissuesPossible candidate biomarkersHigh mortality rateAdjacent tissue samplesVariety of cancersCancer-specific pathwaysLncRNA-mRNA co-expression networkNormal human tissuesEpstein-BarrReal-time PCRLong non-coding RNAsIndependent cohortMortality rateCandidate biomarkersCancerMRNA expressionSNHG8Tissue samplesTumorigenesis mechanismsHuman cancersBody map
2015
Six novel rare non-synonymous mutations for migraine without aura identified by exome sequencing
Jiang Y, Wu R, Chen C, You ZF, Luo X, Wang XP. Six novel rare non-synonymous mutations for migraine without aura identified by exome sequencing. Journal Of Neurogenetics 2015, 29: 188-194. PMID: 26814133, DOI: 10.3109/01677063.2015.1122787.Peer-Reviewed Original ResearchMeSH KeywordsCalcium-Binding ProteinsChloride ChannelsComputational BiologyDNA Mutational AnalysisExomeFamily HealthFemaleGenetic Association StudiesGenetic Predisposition to DiseaseGTPase-Activating ProteinsGTP-Binding ProteinsHumansMaleMembrane GlycoproteinsMigraine without AuraMucinsMutationPolymorphism, Single NucleotideReceptors, G-Protein-CoupledUbiquitin-Conjugating EnzymesXedar ReceptorConceptsNon-synonymous mutationsRare non-synonymous mutationsExome sequencingNovel non-synonymous mutationsBioinformatics analysisX chromosomeMultiple genesCellular responsesWhole-exome sequencingSusceptibility gene mutationsCell membrane potentialARHGAP28MutationsSequencingProteinGBP2Membrane potentialEMR1Gene mutationsChemical factorsCLCNKBChromosomesGenesVasogenic theoryGenetic predisposition
2013
NRG3 gene is associated with the risk and age at onset of Alzheimer disease
Wang KS, Xu N, Wang L, Aragon L, Ciubuc R, Arana TB, Mao C, Petty L, Briones D, Su BB, Luo X, Camarillo C, Escamilla MA, Xu C. NRG3 gene is associated with the risk and age at onset of Alzheimer disease. Journal Of Neural Transmission 2013, 121: 183-192. PMID: 24061483, DOI: 10.1007/s00702-013-1091-0.Peer-Reviewed Original ResearchExome-wide association study of replicable nonsynonymous variants conferring risk for alcohol dependence.
Zuo L, Saba L, Wang K, Zhang X, Krystal JH, Tabakoff B, Luo X. Exome-wide association study of replicable nonsynonymous variants conferring risk for alcohol dependence. Journal Of Studies On Alcohol And Drugs 2013, 74: 622-5. PMID: 23739027, PMCID: PMC3711352, DOI: 10.15288/jsad.2013.74.622.Peer-Reviewed Original ResearchConceptsApolipoprotein E receptor 2Risk genesNonsynonymous variantsRNA expression analysisExome-wide association studyE receptor 2Expression analysisAssociation studiesGenesWhole exomeProtein 2RNA expressionNsSNPReplicable associationsAlcohol dependenceNonhuman speciesEuropean American sampleReceptor 2UbiquitinVariantsMultiple testingSpeciesExomeBioinformaticsUBAP2