2022
Association between plasma levels of BDNF and GDNF and the diagnosis, treatment response in first-episode MDD
Liu X, Li P, Ma X, Zhang J, Sun X, Luo X, Zhang Y. Association between plasma levels of BDNF and GDNF and the diagnosis, treatment response in first-episode MDD. Journal Of Affective Disorders 2022, 315: 190-197. PMID: 35908604, DOI: 10.1016/j.jad.2022.07.041.Peer-Reviewed Original ResearchConceptsAntidepressant treatmentPlasma levelsGDNF levelsMATRICS Consensus Cognitive BatteryMDD patientsHealthy controlsDepression severityWeeks antidepressant treatmentFirst-episode depressionPeripheral plasma levelsPeripheral venous bloodWeeks of treatmentDiagnosis of MDDDecreased plasma levelsHAMA-14Plasma BDNFAntidepressant medicationClinical symptomsHDRS-17Venous bloodCognitive dysfunctionPlasma concentrationsTreatment responseConsensus Cognitive BatteryPatients
2020
Altered brain function and clinical features in patients with first-episode, drug naïve major depressive disorder: A resting-state fMRI study
Liang S, Xue K, Wang W, Yu W, Ma X, Luo S, Zhang J, Sun X, Luo X, Liu F, Zhang Y. Altered brain function and clinical features in patients with first-episode, drug naïve major depressive disorder: A resting-state fMRI study. Psychiatry Research Neuroimaging 2020, 303: 111134. PMID: 32652482, DOI: 10.1016/j.pscychresns.2020.111134.Peer-Reviewed Original ResearchConceptsMajor depressive disorderDrug-naïve major depressive disorderAltered brain functionFunctioning Assessment Short TestMATRICS Consensus Cognitive BatteryMDD patientsDepressive disorderDefault mode networkBrain functionClinical featuresFunctional impairmentHealthy subjectsLow-frequency fluctuation (ALFF) valuesDrug-naïve MDD patientsResting-state fMRI studyAssessment Short TestTotal FAST scoresALFF valuesNeurocognitive impairmentPatientsConsensus Cognitive BatteryLingual gyrusOccupational functioningFAST scoreGlobal functioningPsychometric properties of the MATRICS Consensus Cognitive Battery (MCCB) in Chinese patients with major depressive disorder
Liang S, Yu W, Ma X, Luo S, Zhang J, Sun X, Luo X, Zhang Y. Psychometric properties of the MATRICS Consensus Cognitive Battery (MCCB) in Chinese patients with major depressive disorder. Journal Of Affective Disorders 2020, 265: 132-138. PMID: 32090734, DOI: 10.1016/j.jad.2020.01.052.Peer-Reviewed Original ResearchConceptsMajor depression disorderMATRICS Consensus Cognitive BatteryMDD patientsCognitive impairmentChinese patientsConsensus Cognitive BatteryBipolar disorderHamilton Depression Rating Scale-17Cognitive AssessmentChinese MDD patientsMajor depressive disorderSeverity of symptomsMontreal Cognitive AssessmentConcurrent validityMild cognitive impairmentCognitive batteryPsychometric propertiesGood concurrent validityMedication treatmentDepressive disorderHealthy controlsGood internal consistencyDepressive symptomsDepression disorderPatients